Radiation-induced second malignancies (RISM) is one of the important late side effects of
radiation therapy and has an impact on optimal treatment decision-making. Many factors …

As the population of cancer survivors has increased and continues to age, the occurrence of
second cancers has risen dramatically-from 9% of all cancer diagnoses in 1975-1979 to …

Importance The number of cancer survivors who develop new cancers is projected to
increase, but comprehensive data on the risk of subsequent primary cancers (SPCs) among …

Hodgkin lymphoma (HL) is an uncommon malignancy of B-cell origin. Classical HL (cHL)
and nodular lymphocyte–predominant HL are the 2 main types of HL. The cure rates for HL …

Background The comparative risks of a second cancer diagnosis are uncertain after primary
cancer treatment with 3‐dimensional conformal radiotherapy (3DCRT), intensity‐modulated …

Background Several epidemiological studies have reported increased risks of second lung
cancers after breast cancer irradiation. In this study we assessed the effects of the delivered …

Despite decades of research to understand the biological effects of ionising radiation, there
is still much uncertainty over the role of dose rate. Motivated by a virtual workshop on the …

Objectives The majority of childhood cancer patients now achieve long-term survival, but the
treatments that cured their malignancy often put them at risk of adverse health outcomes …

Tremendous progress in treatment and outcomes has been achieved across the whole
range of haematological malignancies in the past two decades. Although cure rates for …

Background and purpose: Radiotherapy plays an essential role in early breast cancer
treatment, but is also associated with an increased risk of second malignancies decades …