Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …

The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …

Melatonin is known to possess several properties of value for healthy aging, as a direct and
indirect antioxidant, protectant and modulator of mitochondrial function, antiexcitotoxic …

The metabolic syndrome (MS) is a collection of risk factors for cardiovascular disease,
including obesity, hypertension, hyperinsulinemia, glucose intolerance and dyslipidemia …

Obesity results from critical periods of positive energy balance characterized by caloric
intake greater than energy expenditure. This disbalance promotes adipose tissue …

Given the fact that both melatonin and nicotinamide mononucleotide (NMN) act as
pleiotropic agents in various age-related cognitive disorders, we aimed to investigate the …

The aim of this review is to summarize current studies on the relationship between melatonin
and aging. Nowadays, age-related diseases come into prominence, and identifying age …

The eye is continuously exposed to solar UV radiation and pollutants, making it prone to
oxidative attacks. In fact, oxidative damage is a major cause of age‐related ocular diseases …

This study investigated the protective effects of melatonin and folic acid against carbon
tetrachloride (CCl4)-induced hepatic injury in rats. Oxidative stress, liver function, liver …