Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …

The advantages of high-precision dosing, manufacturing efficiency, and patient compliance
make tablets the most popular dosage forms. Compaction, an essential manufacturing step …

It is well known that compression speed can have significant effects on the compaction
properties of pharmaceutical powders. This is a challenge during scale up and technology …

Publisher Summary Particle characterization is an important component of data driven
formulation development on a material-sparing scale. Particle size, size distribution, shape …

The roller compaction process has gained heightened interest in the pharmaceutical
industry. In this review, common excipients and equipment used for dry granulation are …

Capping or lamination is an unsolved common problem in tablet manufacturing. Knowledge
gaps remain despite an enormous amount of effort made in the past to better understand the …

Capping is the frequently observed mechanical defect in tablets arising from the sub-optimal
selection of the formulation composition and their robustness of response toward process …

Purpose The aim of this study was to establish the suitability of terahertz (THz) transmission
measurements to accurately measure and predict the critical quality attributes of …

Internal lubrication can be associated with reduced tabletability. Deformation mechanism,
lubricant type, lubricant blending time and paddle speed (PS) of the forced feeder are known …

Air entrapment during powder compression, a phenomenon that can cause tablet defects
upon decompression and ejection, was diagnosed for celecoxib powder by comparing its in …