The omnipresence and deep impact of artificial intelligence (AI) in today's society are
undeniable. While the technology has already established itself as a powerful tool in several …

Importance Cohort studies have reported increased incidence of cardiovascular disease
(CVD) among individuals with low vitamin D status. To date, randomized clinical trials of …

Background Most cardiovascular disease risk prediction equations in use today were
derived from cohorts established last century and with participants at higher risk but less …

Objective: To assess the clinical relevance of regression to the mean for clinical trials and
clinical practice. Methods: MEDLINE was searched until February 2018 for randomized trials …

Background Non-obstructive coronary artery disease (CAD) on coronary angiography after
myocardial infarction (MI) is associated with a lower risk of adverse outcomes, but the …

Background Until recently, most patients with diabetes worldwide have been diagnosed
when symptomatic and have high cardiovascular risk, meaning most should be prescribed …

Objective To determine whether contemporary sex-specific cardiovascular disease (CVD)
risk prediction equations underestimate CVD risk in people with severe mental illness from …

Objective The medium-term outcome and cause of death in patients with myocardial
infarction with non-obstructive coronary arteries (MINOCA) is not well characterised. The aim …

Background Wide-ranging concerns exist regarding the use of black-box modelling methods
in sensitive contexts such as healthcare. Despite performance gains and hype, uptake of …

Importance A decision to initiate aspirin therapy for primary prevention of cardiovascular
disease (CVD) requires consideration of both treatment benefits and harms. The most …