Evolution of glycolysis

LA Fothergill-Gilmore, PAM Michels - Progress in biophysics and molecular …, 1993 - Elsevier
" Metabolic pathways are boring!" The attitude implicit in this assertion is not uncommon, and
probably arises because pathways are frequently considered to be uninteresting collections …

[HTML][HTML] Metabolic functions of glycosomes in trypanosomatids

PAM Michels, F Bringaud, M Herman… - Biochimica et Biophysica …, 2006 - Elsevier
Protozoan Kinetoplastida, including the pathogenic trypanosomatids of the genera
Trypanosoma and Leishmania, compartmentalize several important metabolic systems in …

[PDF][PDF] Compartmentation of carbohydrate metabolism in trypanosomes

FR Opperdoes - Annual review of microbiology, 1987 - researchgate.net
The protozoan hemoflagellates belonging to the order Kinetoplastida, which comprise the
genera Trypanosoma and Leishmania, are the causative agents of a number of important …

Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis.

CC Wang - Annual Review of Pharmacology and Toxicology, 1995 - europepmc.org
There are only a handful of drugs available today for treating African trypanosomiasis, most
of which were discovered more than forty years ago. These drugs are plagued by various …

Glycolytic enzymes of Trypanosoma brucei Simultaneous purification, intraglycosomal concentrations and physical properties

O MISSET, OJM BOS… - European Journal of …, 1986 - Wiley Online Library
We have developed a method for the simultaneous purification of hexokinase,
glucosephosphate isomerase, phosphofructokinase, fructose‐1, 6‐bisphosphate aldolase …

In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes

FR Opperdoes, JP Szikora - Molecular and Biochemical Parasitology, 2006 - Elsevier
In total, 37080 protein sequences of the three trypanosomatids Leishmania major,
Trypanosoma brucei and Trypanosoma cruzi, were used to predict the trypanosomatid …

Comparative proteomics of glycosomes from bloodstream form and procyclic culture form Trypanosoma brucei brucei

C Colasante, M Ellis, T Ruppert, F Voncken - Proteomics, 2006 - Wiley Online Library
Peroxisomes are present in nearly every eukaryotic cell and compartmentalize a wide range
of important metabolic processes. Glycosomes of Kinetoplastid parasites are peroxisome …

Import of proteins into peroxisomes and other microbodies.

MJ De Hoop, G Ab - Biochemical Journal, 1992 - ncbi.nlm.nih.gov
This review focuses on a particular type of organelle, the microbody. Since its discovery,
about four decades ago, it has become clear that it is involved in a variety ofmetabolic …

Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis

ML Muhich, JC Boothroyd - Molecular and cellular biology, 1988 - Taylor & Francis
Maturation of mRNA precursors in trypanosomes involves an apparent trans splicing event
in which a 39-nucleotide miniexon sequence, common to all trypanosome mRNAs, is joined …

Analysis of the carboxyl-terminal peroxisomal targeting signal 1 in a homologous context in Saccharomyces cerevisiae

Y Elgersma, A Vos, M Van den Berg… - Journal of Biological …, 1996 - ASBMB
Most peroxisomal matrix proteins contain a carboxyl-terminal tripeptide that directs them to
peroxisomes. Within limits, these amino acids may be varied, without loss of function. The …