The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since
become a well-studied therapy for cancer and various non-malignant diseases including …

The use of visible light to produce highly selective and potent drugs through photodynamic
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …

Metal-based drugs have drawn significant attention over the past few decades due to their
advanced properties and benefits in biomedical therapeutic and diagnostic systems. Among …

Increased use of classical drug therapy, including the administration of antibiotics and
anticancer drugs, has led to multidrug resistance. Overcoming this resistance requires …

This Account summarizes the DNA binding properties of anticancer active dinuclear Rh, Re,
and Ru compounds. The combined results of NMR spectroscopy, X-ray crystallography, and …

Photochemical activation is a very attractive way to achieve precise spatial and temporal
control of the biological action of transition‐metal complexes that behave as inactive …

The development of photoactivatable prodrugs of platinum-based antitumor agents is aimed
at increasing the selectivity and hence lowering toxicity of this important class of antitumor …

The cation cis-[Ru (bpy) 2 (5CNU) 2] 2+(bpy= 2, 2′-bipyridine; 5CNU= 5-cyanouracil) was
synthesized and investigated for use as a potential light-activated dual-action therapeutic …

Ru (II) complexes possessing new tridentate ligands with extended π systems, pydppx (3-
(pyrid-2′-yl)-11, 12-dimethyl-dipyrido [3, 2-a: 2′, 3′-c] phenazine) and pydppn (3-(pyrid …