Animals assemble and maintain a diverse but host-specific gut microbial community. In
addition to characteristic microbial compositions along the longitudinal axis of the intestines …

Biofilms are a widely observed growth mode in which microbial communities are spatially
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …

Vibrio cholerae, the causative agent of cholera, requires two coordinately regulated factors
for full virulence: cholera toxin (CT), a potent enterotoxin, and toxin-coregulated pili (TCP) …

Comparative genomics demonstrated that the chromosomes from bacteria and their viruses
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …

The toxR gene of Vibrio cholerae encodes a transmembrane, DNA-binding protein that
activates transcription of the cholera toxin operon and a gene (tcpA) for the major subunit of …

Zimbabwe offers the most recent example of the tragedy that befalls a country and its people
when cholera strikes. The 2008–2009 outbreak rapidly spread across every province and …

Cholera caused by toxigenic Vibrio cholerae is a major public health problem confronting
developing countries, where outbreaks occur in a regular seasonal pattern and are …

In response to the emergence of pathogenic bacteria that cannot be treated with current
antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight …

Isogenic mutant strains of V. cholerae O1 lacking elements of a genetic regulon controlled
by toxR and implicated in virulence were tested in volunteers. A deletion mutation in ctxA …

The marine bacterium Vibrio harveyi possesses two quorum sensing systems (System 1 and
System 2) that regulate bioluminescence. Although the Vibrio cholerae genome sequence …