The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …

Background Shedding light on less-known aspects of intracranial fluid dynamics may be
helpful to understand the hydrocephalus mechanism. The present study suggests a …

Three-D head geometrical models of eight healthy subjects and 11 hydrocephalus patients
were built using their CINE phase-contrast MRI data and used for computer simulations …

The clinical application of intracranial compliance (ICC),∆ V/∆ P, as one of the most critical
indexes for hydrocephalus evaluation was demonstrated previously. We suggest a new …

Background Infusion testing is a common procedure to determine whether shunting will be
beneficial in patients with normal pressure hydrocephalus. The method has a well …

Background Transport of solutes has been observed in the spaces surrounding cerebral
arteries and veins. Indeed, transport has been found in opposite directions in two different …

Current theories suggest that waste solutes are cleared from the brain via cerebrospinal fluid
(CSF) flow, driven by pressure pulsations of possibly both cardiac and respiratory origin. In …

Spinal microstructures are known to substantially affect cerebrospinal fluid patterns, yet their
actual impact on flow resistance has not been quantified. Because the length scale of …

The unpredictable complexities in hydrocephalus shunt outcomes may be related to the
recovery behavior of brain tissue after shunting. The simulated cerebrospinal fluid (CSF) …