Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …

Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers.
Although constituting only 1% of all human malignancies, sarcomas represent the second …

MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …

Idiopathic pulmonary fibrosis (IPF) is characterized by devastating and progressive lung
parenchymal fibrosis, resulting in poor patient prognosis. An aberrant recapitulation of …

Exosomes released by tumor cells have been recently identified as important determinants
of tumor progression. They often carry circular RNAs that are differentially expressed in …

Noncoding RNAs are functional transcripts that are not translated into proteins. They
represent the largest portion of the human transcriptome and have been shown to regulate …

The current diagnosis and treatment of sarcoma continue to show limited timeliness and
efficacy. In order to enable the early detection and management of sarcoma, increasing …

Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with
potential applications during all stages of patient care, from diagnosis to long-term follow-up …

Exosomes mediate cell-to-cell crosstalk involving a variety of biomolecules through an
intricate signaling network. In recent years, the pivotal role of exosomes and their non …

Exosomes, together with their accompanying proteins and nucleic acids have been
increasingly recognized as biomarkers for non-invasive tumor diagnostic and prognostic …