Nicotine, one of the more than 4700 ingredients in tobacco smoke, is a neurotoxin and once
used as pesticides in agriculture. Although its use in agriculture is prohibited in many …

Smoking tobacco products is the leading cause of preventable death worldwide.
Coordinated efforts have successfully reduced tobacco cigarette smoking in the United …

Electronic cigarettes (e-cigarettes), also known as electronic nicotine delivery systems, are a
popular alternative to conventional nicotine cigarettes, both among smokers and those who …

BACKGROUND: Cigarette smoking/nicotine exposure in pregnancy shows an increased risk
of hypertension in offspring, but the mechanisms are unclear. This study tested the …

Electronic cigarettes (E-cig) use is increasing rapidly, particularly among youths. Animal
models for E-cig exposure with pharmacokinetics resembling human E-cig users are …

Background In utero cigarette smoking/nicotine exposure during pregnancy significantly
affects fetal development and increases the risk of cardiovascular disease late in life …

Introduction The distinctions in the biological impacts of distinct forms of nicotine have
become a prominent subject of current research. However, relatively little research has been …

Background A supply of maternal thyroid hormone (thyroxine, T4) is essential for normal
human fetal development. Human placental trophoblasts synthesize, secrete and take up …

Background: β-Nicotyrine (β-Nic) is a unique minor alkaloid constituent in electronic nicotine
delivery systems (ENDS) that is derived from nicotine (Nic) degradation and can reach 25 …

Smoking has become one of the leading causes in preventable deaths in the world,
accounting for approximately 20% of total deaths and 90% of lung cancer. Cigarette …