RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts
The increased application of transcriptome-wide profiling approaches has led to an
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …
explosion in the number of documented long non-coding RNAs (lncRNAs). While these new …
On the classification of long non-coding RNAs
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide
variety of important biological processes. To make easier interpretation of lncRNA …
variety of important biological processes. To make easier interpretation of lncRNA …
Local regulation of gene expression by lncRNA promoters, transcription and splicing
Mammalian genomes are pervasively transcribed, to produce thousands of long non-coding
RNAs (lncRNAs),. A few of these lncRNAs have been shown to recruit regulatory complexes …
RNAs (lncRNAs),. A few of these lncRNAs have been shown to recruit regulatory complexes …
Evolution and functions of long noncoding RNAs
RNA is not only a messenger operating between DNA and protein. Transcription of
essentially the entire eukaryotic genome generates a myriad of non-protein-coding RNA …
essentially the entire eukaryotic genome generates a myriad of non-protein-coding RNA …
Long non-coding RNAs: insights into functions
In mammals and other eukaryotes most of the genome is transcribed in a developmentally
regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we …
regulated manner to produce large numbers of long non-coding RNAs (ncRNAs). Here we …
Long noncoding RNAs: past, present, and future
JTY Kung, D Colognori, JT Lee - Genetics, 2013 - academic.oup.com
Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …
Epigenetics and gene expression
ER Gibney, CM Nolan - Heredity, 2010 - nature.com
Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
KL Yap, S Li, AM Muñoz-Cabello, S Raguz, L Zeng… - Molecular cell, 2010 - cell.com
Expression of the INK4b/ARF/INK4a tumor suppressor locus in normal and cancerous cell
growth is controlled by methylation of histone H3 at lysine 27 (H3K27me) as directed by the …
growth is controlled by methylation of histone H3 at lysine 27 (H3K27me) as directed by the …
Long noncoding RNAs: functional surprises from the RNA world
Most of the eukaryotic genome is transcribed, yielding a complex network of transcripts that
includes tens of thousands of long noncoding RNAs with little or no protein-coding capacity …
includes tens of thousands of long noncoding RNAs with little or no protein-coding capacity …
Transcriptional regulatory functions of nuclear long noncoding RNAs
KW Vance, CP Ponting - Trends in Genetics, 2014 - cell.com
Several nuclear localised intergenic long noncoding RNAs (lncRNAs) have been ascribed
regulatory roles in transcriptional control and their number is growing rapidly. Initially, these …
regulatory roles in transcriptional control and their number is growing rapidly. Initially, these …