GnRH, anosmia and hypogonadotropic hypogonadism–where are we?

PE Forni, S Wray - Frontiers in neuroendocrinology, 2015 - Elsevier
Gonadotropin releasing hormone (GnRH) neurons originate the nasal placode and migrate
into the brain during prenatal development. Once within the brain, these cells become …

Direct and indirect effects of sex steroids on gonadotrope cell plasticity in the teleost fish pituitary

R Fontaine, MR Royan, K Von Krogh… - Frontiers in …, 2020 - frontiersin.org
The pituitary gland controls many important physiological processes in vertebrates,
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …

Evolution of the hypothalamic-pituitary-gonadal axis regulation in vertebrates revealed by knockout medaka

A Takahashi, S Kanda, T Abe, Y Oka - Endocrinology, 2016 - academic.oup.com
Reproduction is essential for life, but its regulatory mechanism is diverse. The analysis of
this diversity should lead us to understand the evolutionary process of the regulation of …

recent applications of gene editing in fish species and aquatic medicine

A Gutási, SE Hammer, M El-Matbouli, M Saleh - Animals, 2023 - mdpi.com
Simple Summary The aquaculture industries are essential sectors of food production and
global trade. Several novel approaches have established gene modification in different fish …

Evolutionally conserved function of kisspeptin neuronal system is nonreproductive regulation as revealed by nonmammalian study

M Nakajo, S Kanda, T Karigo, A Takahashi… - …, 2018 - academic.oup.com
The kisspeptin neuronal system, which consists of a neuropeptide kisspeptin and its
receptor Gpr54, is considered in mammals a key factor of reproductive regulation, the so …

Evolution of the regulatory mechanisms for the hypothalamic-pituitary-gonadal axis in vertebrates–hypothesis from a comparative view

S Kanda - General and comparative endocrinology, 2019 - Elsevier
Reproduction is regulated by the hypothalamic-pituitary-gonadal (HPG) axis in vertebrates.
In addition to wealth of knowledge in mammals, recent studies in non-mammalian species …

Identification of the FSH-RH as the other gonadotropin-releasing hormone

SK Uehara, Y Nishiike, K Maeda, T Karigo… - Nature …, 2024 - nature.com
In vertebrates, folliculogenesis and ovulation are regulated by two distinct pituitary
gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Currently …

Multimodal hypothalamo-hypophysial communication in the vertebrates

VL Trudeau, GM Somoza - General and comparative endocrinology, 2020 - Elsevier
The vertebrate pituitary is arguably one of the most complex endocrine glands from the
evolutionary, anatomical and functional perspectives. The pituitary plays a master role in …

[HTML][HTML] Association of long-term effects of low-level sulfamethoxazole with ovarian lipid and amino acid metabolism, sex hormone levels, and oocyte maturity in …

K Yu, Y Qiu, Y Shi, X Yu, T Dong, Y Wu, H Li… - … and Environmental Safety, 2022 - Elsevier
Sulfamethoxazole (SMZ) is an important antibiotic used to prevent and treat infections in
both clinical settings and animal husbandry. High levels of SMZ may exhibit endocrine …

Differential regulation of gonadotropins as revealed by transcriptomes of distinct LH and FSH cells of fish pituitary

L Hollander-Cohen, M Golan… - International Journal of …, 2021 - mdpi.com
From mammals to fish, reproduction is driven by luteinizing hormone (LH) and follicle-
stimulating hormone (FSH) temporally secreted from the pituitary gland. Teleost fish are an …