As an essential component of innate immunity, macrophages have multiple functions in both
inhibiting or promoting cell proliferation and tissue repair. Diversity and plasticity are …

Monocytes are considered to be precursor cells of the mononuclear phagocytic system, and
macrophages are one of the leading members of this cellular system. Macrophages play …

Background Surrogate biomarkers of efficacy are needed for anti-PD1/PD-L1 therapy, given
the existence of delayed responses and pseudo-progressions. We evaluated changes in …

Tumor-associated macrophages (TAMs) play a central role in tumor progression, metastasis,
and recurrence after treatment. Macrophage plasticity and diversity allow their classification …

Prognostic significance of tumor-associated macrophages in breast cancer: a meta-analysis of
the literature - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Simple Summary Hepatocellular carcinoma (HCC) constitutes a major health burden,
accounting for> 80% of primary liver cancers globally. Inflammation has come into the …

Purpose: Myeloid-derived suppressor cells (MDSC) are considered an important T-cell
immunosuppressive component in cancer-bearing hosts. The factors that attract these cells …

Metabolic reprogramming is critical for the polarization and function of tumor-associated
macrophages (TAM) and hepatocarcinogenesis, but how this reprogramming occurs is …

As humans evolved, perhaps the two strongest selection determinants of survival were a
robust immune response able to clear bacterial, viral, and parasitic infection and an ability to …

Cholangiocarcinoma (CCA) is a malignancy with features of the biliary epithelium. Although
CCA is recognized as a rare cancer, it is the second most common primary liver tumor after …