Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
C Qin, S Yang, YH Chu, H Zhang, XW Pang… - Signal transduction and …, 2022 - nature.com
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces
severe neural injuries, and is one of the leading causes of death and disability worldwide …
severe neural injuries, and is one of the leading causes of death and disability worldwide …
Neuroinflammation: friend and foe for ischemic stroke
RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …
perspective with the emergence of new ideas on neurodegeneration. The concept that …
The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …
which initiates rapid signal transmission in the synapse before its re-uptake into the …
The role of glutamate receptors in epilepsy
TS Chen, TH Huang, MC Lai, CW Huang - Biomedicines, 2023 - mdpi.com
Glutamate is an essential excitatory neurotransmitter in the central nervous system, playing
an indispensable role in neuronal development and memory formation. The dysregulation of …
an indispensable role in neuronal development and memory formation. The dysregulation of …
[HTML][HTML] Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders
N Singewald, C Schmuckermair, N Whittle… - Pharmacology & …, 2015 - Elsevier
Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …
Role of glutamate excitotoxicity and glutamate transporter EAAT2 in epilepsy: Opportunities for novel therapeutics development
JL Green, WF Dos Santos, ACK Fontana - Biochemical pharmacology, 2021 - Elsevier
Epilepsy is a complex neurological syndrome characterized by seizures resulting from
neuronal hyperexcitability and sudden and synchronized bursts of electrical discharges …
neuronal hyperexcitability and sudden and synchronized bursts of electrical discharges …
[HTML][HTML] Worldwide flavor enhancer monosodium glutamate combined with high lipid diet provokes metabolic alterations and systemic anomalies: An overview
A Banerjee, S Mukherjee, BK Maji - Toxicology Reports, 2021 - Elsevier
In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …
activities that ultimately change their food habits. Majorities of such foods have harmful …
The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies
W Hu, ML MacDonald, DE Elswick… - Annals of the New York …, 2015 - Wiley Online Library
A number of studies have indicated that antagonists of the N‐methyl‐d‐aspartate subtypes
of glutamate receptors can cause schizophrenia‐like symptoms in healthy individuals and …
of glutamate receptors can cause schizophrenia‐like symptoms in healthy individuals and …
Astrocytic oxidative/nitrosative stress contributes to Parkinson's disease pathogenesis: the dual role of reactive astrocytes
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide; it is characterized by dopaminergic neurodegeneration in the substantia nigra …
worldwide; it is characterized by dopaminergic neurodegeneration in the substantia nigra …
Monosodium glutamate-induced oxidative kidney damage and possible mechanisms: a mini-review
A Sharma - Journal of biomedical science, 2015 - Springer
Animal studies suggest that chronic monosodium glutamate (MSG) intake induces kidney
damage by oxidative stress. However, the underlying mechanisms are still unclear, despite …
damage by oxidative stress. However, the underlying mechanisms are still unclear, despite …