Lactate dehydrogenase (LDH) is one of the crucial enzymes in aerobic glycolysis, catalyzing
the last step of glycolysis, ie. the conversion of pyruvate to lactate. Most cancer cells are …

Impaired cognition is the primary symptom of dementia, which can lead to functional
disability and reduced quality of life among an increasingly ageing population. Ageing is …

Intestinal inflammation and dysbiosis can lead to inflammatory bowel diseases (IBD) and
systemic inflammation, affecting multiple organs. Developing novel anti-inflammatory …

Background The main cause of high mortality from sepsis is that immunosuppression leads
to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis …

Ethnopharmacological relevance Numerous studies have demonstrated that various
traditional Chinese medicines (TCMs) exhibit potent anti-inflammatory effects against …

Capsaicin is the main pungent compound in red pepper responsible for its dual attributes of
culinary utility and bioactive efficacy. This review aims to systematically review the …

Background In sepsis, the lungs are one of the most severely affected organs, usually
resulting in acute lung injury (ALI). Capsaicin (CAP) is a natural compound found in chili …

Capsaicin, the most prominent pungent compound of chilli peppers, has been used in
traditional medicine systems for centuries; it already has a number of established clinical …

Many energy metabolism pathways exist in cancer, including glycolysis, amino acid
metabolism, fatty acid oxidation, and mitochondrial respiration. Tumor cells mainly generate …

Inflammation plays a pivotal role in the development and progression of inflammatory bowel
disease (IBD), by contributing to tissue damage and exacerbating the immune response …