Electrochemical methods for the analysis of clinically relevant biomolecules
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …
demand for high-performance detection technologies. Implementation of electrochemical …
Circulating tumor DNA and liquid biopsy: opportunities, challenges, and recent advances in detection technologies
Cell-free DNA (cfDNA) refers to short fragments of acellular nucleic acids detectable in
almost all body fluids, including blood, and is involved in various physiological and …
almost all body fluids, including blood, and is involved in various physiological and …
Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …
Functional DNA nanostructures for theranostic applications
H Pei, X Zuo, D Zhu, Q Huang… - Accounts of chemical …, 2014 - ACS Publications
There has been tremendous interest in constructing nanostructures by exploiting the
unparalleled ability of DNA molecules in self-assembly. We have seen the appearance of …
unparalleled ability of DNA molecules in self-assembly. We have seen the appearance of …
Electrochemical sensors
This review covers scholarly articles published in 2008 and 2009 related to the field of
electrochemical sensors. Emphasis was given to full papers reporting on fundamental …
electrochemical sensors. Emphasis was given to full papers reporting on fundamental …
Binary probes for nucleic acid analysis
DM Kolpashchikov - Chemical reviews, 2010 - ACS Publications
Over the last four decades nucleic acid hybridization techniques have been widely used for
the detection of specific nucleic acid sequences. In this approach a 15-nucleotide or longer …
the detection of specific nucleic acid sequences. In this approach a 15-nucleotide or longer …
Triple-helix molecular switch electrochemical ratiometric biosensor for ultrasensitive detection of nucleic acids
E Xiong, Z Li, X Zhang, J Zhou, X Yan, Y Liu… - Analytical …, 2017 - ACS Publications
Biomolecular receptors such as nucleic acids that switch between two or more
conformations upon binding to a specific target can be used to build specific and sensitive …
conformations upon binding to a specific target can be used to build specific and sensitive …
Detecting DNA and RNA and differentiating single-nucleotide variations via field-effect transistors
We detect short oligonucleotides and distinguish between sequences that differ by a single
base, using label-free, electronic field-effect transistors (FETs). Our sensing platform utilizes …
base, using label-free, electronic field-effect transistors (FETs). Our sensing platform utilizes …
Highly specific SNP detection using 2D graphene electronics and DNA strand displacement
Single-nucleotide polymorphisms (SNPs) in a gene sequence are markers for a variety of
human diseases. Detection of SNPs with high specificity and sensitivity is essential for …
human diseases. Detection of SNPs with high specificity and sensitivity is essential for …
Paper electrochemical device for detection of DNA and thrombin by target-induced conformational switching
JC Cunningham, NJ Brenes, RM Crooks - Analytical chemistry, 2014 - ACS Publications
Here, we report a strategy for the design of an inexpensive paper analytical device (PAD) for
quantitative detection of oligonucleotides and proteins. Detection is based on the principle of …
quantitative detection of oligonucleotides and proteins. Detection is based on the principle of …