Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Mass spectrometry imaging (MSI) is an emerging technology in cancer metabolomics.
Desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization …

Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Mass spectrometry imaging (MSI) has accelerated our understanding of lipid metabolism
and spatial distribution in tissues and cells. However, few MSI studies have approached lipid …

Simple Summary Cancer is the leading cause of death worldwide, and the overall aging of
the population results in an increased risk of a cancer diagnosis during a person's lifetime …

Solid tumors have a dynamic ecosystem in which malignant and non-malignant (endothelial,
stromal, and immune) cell types constantly interact. Importantly, the abundance, localization …

The integration of spatial omics technologies can provide important insights into the biology
of tissues. Here we combined mass spectrometry imaging-based metabolomics and imaging …

Mass spectrometry imaging has advanced from a niche technique to a widely applied spatial
biology tool operating at the forefront of numerous fields, most notably making a significant …

Currently, the study of resistance mechanisms and disease progression in cancer relies on
the capacity to analyze tumors as a complex ecosystem of healthy and malignant cells …

The landscape of tissue-based imaging modalities is constantly and rapidly evolving. While
formalin-fixed, paraffin-embedded material is still useful for histological imaging, the fixation …