We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Sperm DNA damage is prevalent among infertile men and is known to influence natural
reproduction. However, the impact of sperm DNA damage on assisted reproduction …

To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

The clinical effect of sperm DNA damage in assisted reproduction has been a controversial
topic during recent decades, leading to a variety of clinical practice recommendations. While …

BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …

STUDY QUESTION Does microfluidic sorting improve the selection of sperm with lower DNA
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …

Reproductive diseases have become a growing worldwide problem and male factor plays
an important role in the reproductive diagnosis, prognosis and design of assisted …

Objective To identify the most robust molecular biomarkers in sperm and seminal plasma for
the diagnosis of male infertility, and to evaluate their clinical use. Design Systematic review …

Background Sperm chromatin integrity is essential for normal embryo development and
pregnancy outcome. Sperm DNA fragmentation (SDF) testing constitutes a diagnostic tool to …

Objective To analyze the effect of single-and double-stranded sperm DNA fragmentation
(ssSDF and dsSDF) on human embryo kinetics monitored under a time-lapse system …