Dendritic cell regulation of T helper cells
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …
Human dendritic cell subsets: an update
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …
haematopoiesis that form an essential interface between the innate sensing of pathogens …
Microenvironment‐responsive prodrug‐induced pyroptosis boosts cancer immunotherapy
Y Xiao, T Zhang, X Ma, QC Yang, LL Yang… - Advanced …, 2021 - Wiley Online Library
The absence of tumor antigens leads to a low response rate, which represents a major
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …
Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy
TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
T cell activation and effector differentiation. They are, likewise, involved in the induction and …
Regional specialization within the intestinal immune system
AM Mowat, WW Agace - Nature Reviews Immunology, 2014 - nature.com
The intestine represents the largest compartment of the immune system. It is continually
exposed to antigens and immunomodulatory agents from the diet and the commensal …
exposed to antigens and immunomodulatory agents from the diet and the commensal …
Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny
The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …
Mapping the human DC lineage through the integration of high-dimensional techniques
INTRODUCTION Dendritic cells (DC) are professional antigen-presenting cells that
orchestrate immune responses. The human DC population comprises multiple subsets …
orchestrate immune responses. The human DC population comprises multiple subsets …
Aryl hydrocarbon receptor controls monocyte differentiation into dendritic cells versus macrophages
After entering tissues, monocytes differentiate into cells that share functional features with
either macrophages or dendritic cells (DCs). How monocyte fate is directed toward …
either macrophages or dendritic cells (DCs). How monocyte fate is directed toward …
Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align …
potential. Multiple DC subsets have been described, and it remains challenging to align …
In vivo Differentiation of Human Monocytes
A Coillard, E Segura - Frontiers in immunology, 2019 - frontiersin.org
Circulating monocytes can infiltrate mucosal or inflamed tissues where they differentiate into
either macrophages or dendritic cells. This paradigm is supported by numerous studies …
either macrophages or dendritic cells. This paradigm is supported by numerous studies …