Dendritic cell regulation of T helper cells

X Yin, S Chen, SC Eisenbarth - Annual review of immunology, 2021 - annualreviews.org
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

Human dendritic cell subsets: an update

M Collin, V Bigley - Immunology, 2018 - Wiley Online Library
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Microenvironment‐responsive prodrug‐induced pyroptosis boosts cancer immunotherapy

Y Xiao, T Zhang, X Ma, QC Yang, LL Yang… - Advanced …, 2021 - Wiley Online Library
The absence of tumor antigens leads to a low response rate, which represents a major
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …

Human dendritic cells: their heterogeneity and clinical application potential in cancer immunotherapy

TA Patente, MP Pinho, AA Oliveira… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DC) are professional antigen presenting cells, uniquely able to induce naïve
T cell activation and effector differentiation. They are, likewise, involved in the induction and …

Regional specialization within the intestinal immune system

AM Mowat, WW Agace - Nature Reviews Immunology, 2014 - nature.com
The intestine represents the largest compartment of the immune system. It is continually
exposed to antigens and immunomodulatory agents from the diet and the commensal …

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

M Guilliams, F Ginhoux, C Jakubzick, SH Naik… - Nature Reviews …, 2014 - nature.com
The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …

Mapping the human DC lineage through the integration of high-dimensional techniques

P See, CA Dutertre, J Chen, P Günther, N McGovern… - Science, 2017 - science.org
INTRODUCTION Dendritic cells (DC) are professional antigen-presenting cells that
orchestrate immune responses. The human DC population comprises multiple subsets …

Aryl hydrocarbon receptor controls monocyte differentiation into dendritic cells versus macrophages

C Goudot, A Coillard, AC Villani, P Gueguen, A Cros… - Immunity, 2017 - cell.com
After entering tissues, monocytes differentiate into cells that share functional features with
either macrophages or dendritic cells (DCs). How monocyte fate is directed toward …

Unsupervised high-dimensional analysis aligns dendritic cells across tissues and species

M Guilliams, CA Dutertre, CL Scott, N McGovern… - Immunity, 2016 - cell.com
Dendritic cells (DCs) are professional antigen-presenting cells that hold great therapeutic
potential. Multiple DC subsets have been described, and it remains challenging to align …

In vivo Differentiation of Human Monocytes

A Coillard, E Segura - Frontiers in immunology, 2019 - frontiersin.org
Circulating monocytes can infiltrate mucosal or inflamed tissues where they differentiate into
either macrophages or dendritic cells. This paradigm is supported by numerous studies …