ELECTROGENIC Na+/HCO 3 COTRANSPORTERS: Cloning and Physiology

MF Romero, WF Boron - Annual Review of Physiology, 1999 - annualreviews.org
▪ Abstract Bicarbonate and CO2 comprise the major pH buffer of biological fluids. In the renal
proximal tubule most of the filtered HCO− 3 is reabsorbed by an electrogenic Na/HCO3 …

The physiology and pathophysiology of pancreatic ductal secretion: the background for clinicians

P Pallagi, P Hegyi, Z Rakonczay Jr - Pancreas, 2015 - journals.lww.com
The human exocrine pancreas consists of 2 main cell types: acinar and ductal cells. These
exocrine cells interact closely to contribute to the secretion of pancreatic juice. The most …

Expression cloning and characterization of a renal electrogenic Na+ /HCO3 cotransporter

MF Romero, MA Hediger, EL Boulpaep, WF Boron - Nature, 1997 - nature.com
Bicarbonate transporters are the principal regulators of pH in animal cells, and play a vital
role in acid–base movement in the stomach, pancreas, intestine, kidney, reproductive …

[HTML][HTML] Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter

N Abuladze, I Lee, D Newman, J Hwang… - Journal of Biological …, 1998 - ASBMB
We report the cloning, sequence analysis, tissue distribution, functional expression, and
chromosomal localization of the human pancreatic sodium bicarbonate cotransport protein …

Bicarbonate transport proteins

D Sterling, JR Casey - Biochemistry and Cell Biology, 2002 - cdnsciencepub.com
Le bicarbonate ne diffuse pas librement au travers des membranes. Cependant, le
bicarbonate doit passer au travers des membranes, car il participe au métabolisme du CO2 …

Na+:HCO3 Cotransporters (NBC): Cloning and Characterization

M Soleimani, CE Burnham - The Journal of membrane biology, 2001 - Springer
The sodium bicarbonate cotransporter (NBC1) is essential for bicarbonate transport across
plasma membranes in epithelial and nonepithelial cells. The direction of the NaHCO 3 …

[HTML][HTML] Physiologic and molecular aspects of the Na+: HCO3-cotransporter in health and disease processes

M Soleimani, CE Burnham - Kidney international, 2000 - Elsevier
Physiologic and molecular aspects of the Na+: HCO 3-cotransporter in health and disease
processes. Approximately 80% of the filtered load of HCO 3-is reabsorbed in the proximal …

[HTML][HTML] Molecular mechanism of regulation of villus cell Na-K-ATPase in the chronically inflamed mammalian small intestine

P Saha, P Manoharan, S Arthur, S Sundaram… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Na-K-ATPase located on the basolateral membrane (BLM) of intestinal epithelial cells
provides a favorable intracellular Na+ gradient to promote all Na dependent co-transport …

Intestinal ion transport in NKCC1-deficient mice

BR Grubb, E Lee, AJ Pace, BH Koller… - American Journal of …, 2000 - journals.physiology.org
The Na+-K+-2Cl− cotransporter (NKCC1) located on the basolateral membrane of intestinal
epithelia has been postulated to be the major basolateral Cl− entry pathway. With targeted …

Mechanisms of oxalate absorption and secretion across the rabbit distal colon

M Hatch, RW Freel, ND Vaziri - Pflügers Archiv, 1994 - Springer
To further evaluate the mechanisms of oxalate (Ox 2−) transport in the intestine the following
studies were performed using isolated, short-circuited segments of the rabbit distal colon …