Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Cells are exposed to a variety of mechanical cues, including forces from their local
environment and physical properties of the tissue. These mechanical cues regulate a vast …

Organ morphogenesis involves dynamic changes of tissue properties while cells adapt to
their mechanical environment through mechanosensitive pathways. How mechanical cues …

Biophysical and biochemical cues work in concert to regulate angiogenesis. These cues
guide angiogenesis during development and wound healing. Abnormal cues contribute to …

Calcific aortic valve disease (CAVD) is a common acquired valvulopathy, which carries a
high burden of mortality. Chronic inflammation has been postulated as the predominant …

Viscoelasticity and its alteration in time and space has turned out to act as a key element in
fundamental biological processes in living systems, such as morphogenesis and motility …

The mechanical regulation of Notch signaling is an emerging area of interest in cell biology.
Notch is essential in many physiological processes in which mechanical stress plays an …

Severe cardiac remodeling leading to heart failure in individuals harboring pathogenic
LMNA variants, known as cardiolaminopathy, poses a significant clinical challenge …

Cardiovascular diseases (CVDs) are a major cause of death worldwide, leading to
increased medical care costs. To turn the scale, it is essential to acquire a more in-depth and …

Extracellular biophysical properties have particular implications for a wide spectrum of
cellular behaviors and functions, including growth, motility, differentiation, apoptosis, gene …