In any gamma-ray detector, each event produces electrical signals on one or more circuit
elements. From these signals, we may wish to determine the presence of an interaction; …

A fast search algorithm capable of operating in multi-dimensional spaces is introduced. As a
sample application, we demonstrate its utility in the 2D and 3D maximum-likelihood position …

High-energy (> 100 keV) photon detectors are often made thick relative to their lateral
resolution in order to improve their photon-detection efficiency. To avoid issues of parallax …

We have previously reported on continuous miniature crystal element (cMiCE) PET
detectors that provide depth of interaction (DOI) positioning capability. A key component of …

We report on a high resolution, monolithic crystal PET detector design concept that provides
depth of interaction (DOI) positioning within the crystal. Our design utilizes a novel sensor on …

Current thick detectors used in medical imaging allow recording many attributes, such as the
3D location of interaction within the scintillation crystal and the amount of energy deposited …

Background Gamma camera imaging, including single photon emission computed
tomography (SPECT), is crucial for research, diagnostics, and radionuclide therapy. Gamma …

Imaging systems are often modeled as continuous-to-discrete mappings that map the object
(ie a function of continuous variables such as space, time, energy, wavelength, etc) to a finite …

We have designed, developed, and assessed a novel preclinical positron emission
tomography (PET) imaging system named ModPET. The system was developed using …

This dissertation addresses the design, development, calibration and performance
evaluation of a pre-clinical imaging system called AdaptiSPECT. Single-Photon Emission …