Cobalt metabolism and toxicology—a brief update

LO Simonsen, H Harbak, P Bennekou - Science of the Total Environment, 2012 - Elsevier
Cobalt metabolism and toxicology are summarized. The biological functions of cobalt are
updated in the light of recent understanding of cobalt interference with the sensing in almost …

[HTML][HTML] Erythropoietin (EPO) in acute kidney injury

E Moore, R Bellomo - Annals of intensive care, 2011 - Springer
Abstract Erythropoietin (EPO) is a 30.4 kDa glycoprotein produced by the kidney, and is
mostly well-known for its physiological function in regulating red blood cell production in the …

Oxidative stress: Biomarkers and novel therapeutic pathways

K Maiese, ZZ Chong, J Hou, YC Shang - Experimental gerontology, 2010 - Elsevier
Oxidative stress significantly impacts multiple cellular pathways that can lead to the initiation
and progression of varied disorders throughout the body. It therefore becomes imperative to …

Erythropoietin and oxidative stress

K Maiese, ZZ Chong, J Hou… - Current Neurovascular …, 2008 - ingentaconnect.com
Unmitigated oxidative stress can lead to diminished cellular longevity, accelerated aging,
and accumulated toxic effects for an organism. Current investigations further suggest the …

Production and characterization of novel chitosan nanoparticles for controlled release of rHu-Erythropoietin

C Bulmer, A Margaritis, A Xenocostas - Biochemical engineering journal, 2012 - Elsevier
In this work we report the production and characterization of nanoparticles using the
ionotropic gelation method between the biopolymer chitosan (CS) and tripolyphosphate …

Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies

K Maiese, ZZ Chong, F Li, YC Shang - Progress in Neurobiology, 2008 - Elsevier
Given that erythropoietin (EPO) is no longer believed to have exclusive biological activity in
the hematopoietic system, EPO is now considered to have applicability in a variety of …

[HTML][HTML] Blood transfusion safety; current status and challenges in Nigeria

JC Aneke, CE Okocha - Asian journal of transfusion science, 2017 - journals.lww.com
The attainment of blood transfusion safety in Nigeria (and probably the rest of Sub-Saharan
Africa) remains an uphill task due to a number of factors, ranging from shortage of blood …

[HTML][HTML] Roles of the kidney in the formation, remodeling and repair of bone

K Wei, Z Yin, Y Xie - Journal of nephrology, 2016 - Springer
The relationship between the kidney and bone is highly complex, and the kidney plays an
important role in the regulation of bone development and metabolism. The kidney is the …

Potential biomarkers in diabetic retinopathy

KM Adki, YA Kulkarni - Current Diabetes Reviews, 2020 - ingentaconnect.com
Background: Diabetic retinopathy is one of the important complications of diabetes. In major
cases, diabetic retinopathy is unnoticed until the irreversible damage to eye occurs and …

Triple play: Promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus

K Maiese - Biomedicine & pharmacotherapy, 2008 - Elsevier
Oxidative stress is a principal pathway for the dysfunction and ultimate destruction of cells in
the neuronal and vascular systems for several disease entities, not promoting the ravages of …