Photofrin® was first approved in the 1990s as a sensitizer for use in treating cancer via
photodynamic therapy (PDT). Since then a wide variety of dye sensitizers have been …

Rose Bengal is an anionic xanthene dye, a derivative of fluorescein, born in the 19th century
as a textile dye; to date, it is known primarily in ophthalmology as a diagnostic tool and …

A highly efficient multifunctional nanoplatform for simultaneous upconversion luminescence
(UCL) imaging and photodynamic therapy has been developed on the basis of selective …

Acrylamide (ACR) is a potent neurotoxic in human and animal models. In this study, the
effect of crocin, main constituent of Crocus sativus L.(Saffron) on ACR-induced cytotoxicity …

Exploring the advanced techniques for protein detection facilitates cell fate investigation.
However, it remains challenging to quantify and visualize the protein with one single probe …

Photodynamic therapy (PDT) could be highly selective and noninvasive, with low side
effects as an adjuvant therapy for cancer treatment. Because excitation sources such as UV …

Saffron (Crocus sativus), widely used as a spice in Middle Eastern cuisine and is known for
anti-cancer properties. The mechanism of saffron-induced cytotoxicity, in tumor cells has not …

Diabetic neuropathy is one of the most frequent complications of diabetes. Despite some
studies, the exact mechanism of glucose neurotoxicity has not been fully elucidated …

Cutaneous melanoma is one of the most aggressive and metastatic forms of skin cancer.
However, current therapeutic options present several limitations, and the annual death rate …

Sono-Photodynamic therapy (SPDT) utilizing ultrasound and light has been demonstrated
that this novel approach can lower dosage resulting in reduction of the potential side effects …