The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as potential …

H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …

The synapse in traumatic brain injury

AAB Jamjoom, J Rhodes, PJD Andrews, SGN Grant - Brain, 2021 - academic.oup.com
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide and is a risk
factor for dementia later in life. Research into the pathophysiology of TBI has focused on the …

Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss

AM Nikolakopoulou, A Montagne, K Kisler, Z Dai… - Nature …, 2019 - nature.com
Pericytes are positioned between brain capillary endothelial cells, astrocytes and neurons.
They degenerate in multiple neurological disorders. However, their role in the pathogenesis …

Pathophysiological responses and roles of astrocytes in traumatic brain injury

S Michinaga, Y Koyama - International journal of molecular sciences, 2021 - mdpi.com
Traumatic brain injury (TBI) is immediate damage caused by a blow to the head resulting
from traffic accidents, falls, and sporting activity, which causes death or serious disabilities in …

Criteria to define mild, moderate, and severe traumatic brain injury in the mouse controlled cortical impact model

L Siebold, A Obenaus, R Goyal - Experimental neurology, 2018 - Elsevier
Traumatic brain injury (TBI) is a major health concern in the United States resulting in a
substantial number of hospitalizations and in a broad spectrum of symptoms and disabilities …

Neuronal‐glial interactions maintain chronic neuropathic pain after spinal cord injury

YS Gwak, CE Hulsebosch, JW Leem - Neural plasticity, 2017 - Wiley Online Library
The hyperactive state of sensory neurons in the spinal cord enhances pain transmission.
Spinal glial cells have also been implicated in enhanced excitability of spinal dorsal horn …

Neuromodulation of glial function during neurodegeneration

R Stevenson, E Samokhina, I Rossetti… - Frontiers in Cellular …, 2020 - frontiersin.org
Glia, a non-excitable cell type once considered merely as the connective tissue between
neurons, is nowadays acknowledged for its essential contribution to multiple physiological …

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

GE Tyzack, CE Hall, CR Sibley, T Cymes… - Nature …, 2017 - nature.com
Astrocyte responses to neuronal injury may be beneficial or detrimental to neuronal
recovery, but the mechanisms that determine these different responses are poorly …

Cell adhesion molecules regulating astrocyte–neuron interactions

CX Tan, C Eroglu - Current opinion in neurobiology, 2021 - Elsevier
A tripartite synapse comprises a neuronal presynaptic axon and a postsynaptic dendrite,
which are closely ensheathed by a perisynaptic astrocyte process. Through their structural …

[HTML][HTML] Cell adhesion and matricellular support by astrocytes of the tripartite synapse

AEJ Hillen, JPH Burbach, EM Hol - Progress in neurobiology, 2018 - Elsevier
Astrocytes contribute to the formation, function, and plasticity of synapses. Their processes
enwrap the neuronal components of the tripartite synapse, and due to this close interaction …