[HTML][HTML] Understanding'non-genetic'inheritance: insights from molecular-evolutionary crosstalk

I Adrian-Kalchhauser, SE Sultan, LNS Shama… - Trends in ecology & …, 2020 - cell.com
Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Evolution of DNA methylome diversity in eukaryotes

A de Mendoza, R Lister, O Bogdanovic - Journal of Molecular Biology, 2020 - Elsevier
Cytosine DNA methylation (5mC) is a widespread base modification in eukaryotic genomes
with critical roles in transcriptional regulation. In recent years, our understanding of 5mC has …

Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species

J Klughammer, D Romanovskaia, A Nemc… - Nature …, 2023 - nature.com
Methylation of cytosines is a prototypic epigenetic modification of the DNA. It has been
implicated in various regulatory mechanisms across the animal kingdom and particularly in …

The emergence of the brain non-CpG methylation system in vertebrates

A de Mendoza, D Poppe, S Buckberry… - Nature ecology & …, 2021 - nature.com
Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …

Tracing animal genomic evolution with the chromosomal-level assembly of the freshwater sponge Ephydatia muelleri

NJ Kenny, WR Francis, RE Rivera-Vicéns… - Nature …, 2020 - nature.com
The genomes of non-bilaterian metazoans are key to understanding the molecular basis of
early animal evolution. However, a full comprehension of how animal-specific traits, such as …

Population epigenetics: The extent of DNA methylation variation in wild animal populations

V Chapelle, F Silvestre - Epigenomes, 2022 - mdpi.com
Population epigenetics explores the extent of epigenetic variation and its dynamics in
natural populations encountering changing environmental conditions. In contrast to …

Sequence determinants, function, and evolution of CpG islands

A Angeloni, O Bogdanovic - Biochemical Society Transactions, 2021 - portlandpress.com
In vertebrates, cytosine-guanine (CpG) dinucleotides are predominantly methylated, with∼
80% of all CpG sites containing 5-methylcytosine (5mC), a repressive mark associated with …

Intergenerational transfer of DNA methylation marks in the honey bee

B Yagound, EJ Remnant… - Proceedings of the …, 2020 - National Acad Sciences
The evolutionary significance of epigenetic inheritance is controversial. While epigenetic
marks such as DNA methylation can affect gene function and change in response to …

Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

SH Lewis, L Ross, SA Bain, E Pahita, SA Smith… - PLoS …, 2020 - journals.plos.org
Cytosine methylation is an ancient epigenetic modification yet its function and extent within
genomes is highly variable across eukaryotes. In mammals, methylation controls …

DNA methylation enables recurrent endogenization of giant viruses in an animal relative

LA Sarre, IV Kim, V Ovchinnikov, M Olivetta, H Suga… - Science …, 2024 - science.org
5-Methylcytosine (5mC) is a widespread silencing mechanism that controls genomic
parasites. In eukaryotes, 5mC has gained complex roles in gene regulation beyond parasite …