In vivo imaging of neuroinflammation in schizophrenia
In recent years evidence has accumulated to suggest that neuroinflammation might be an
early pathology of schizophrenia that later leads to neurodegeneration, yet the exact role in …
early pathology of schizophrenia that later leads to neurodegeneration, yet the exact role in …
Translating the MAM model of psychosis to humans
Elevated dopamine function and alterations in medial temporal lobe (MTL) structure and
function are two of the most robust findings in schizophrenia, but how interactions between …
function are two of the most robust findings in schizophrenia, but how interactions between …
Does the dopamine hypothesis explain schizophrenia?
CI Lau, HC Wang, JL Hsu, ME Liu - Reviews in the Neurosciences, 2013 - degruyter.com
The dopamine hypothesis has been the cornerstone in the research and clinical practice of
schizophrenia. With the initial emphasis on the role of excessive dopamine, the hypothesis …
schizophrenia. With the initial emphasis on the role of excessive dopamine, the hypothesis …
Chronic social isolation decreases glutamate and glutamine levels and induces oxidative stress in the rat hippocampus
Y Shao, G Yan, Y Xuan, H Peng, QJ Huang… - Behavioural brain …, 2015 - Elsevier
Social isolation (SI) rearing of rodents is a developmental manipulation, which is commonly
compared with the psychological stressors in humans as it produces several behavioral …
compared with the psychological stressors in humans as it produces several behavioral …
[HTML][HTML] Magnetic resonance spectroscopy in schizophrenia: evidence for glutamatergic dysfunction and impaired energy metabolism
JMN Duarte, L Xin - Neurochemical research, 2019 - Springer
In the past couple of decades, major efforts were made to increase reliability of metabolic
assessments by magnetic resonance methods. Magnetic resonance spectroscopy (MRS) …
assessments by magnetic resonance methods. Magnetic resonance spectroscopy (MRS) …
Neuroimaging for psychotherapy research: current trends
CP Weingarten, TJ Strauman - Psychotherapy Research, 2015 - Taylor & Francis
Objective: This article reviews neuroimaging studies that inform psychotherapy research. An
introduction to neuroimaging methods is provided as background for the increasingly …
introduction to neuroimaging methods is provided as background for the increasingly …
[HTML][HTML] Impact of glutamate levels on neuronal response and cognitive abilities in schizophrenia
LE Falkenberg, R Westerhausen, AR Craven… - NeuroImage: Clinical, 2014 - Elsevier
Schizophrenia is characterized by impaired cognitive functioning, and brain regions
involved in cognitive control processes show marked glutamatergic abnormalities. However …
involved in cognitive control processes show marked glutamatergic abnormalities. However …
[HTML][HTML] Metabolite differences in the medial prefrontal cortex in schizophrenia patients with and without persistent auditory verbal hallucinations: a 1H MRS study
Q Wang, H Ren, C Li, Z Li, J Li, H Li, L Dai… - Translational …, 2022 - nature.com
Studies of schizophrenia (SCZ) have associated auditory verbal hallucinations (AVH) with
structural and functional abnormalities in frontal cortex, especially medial prefrontal cortex …
structural and functional abnormalities in frontal cortex, especially medial prefrontal cortex …
Association of cortical glutamate and working memory activation in patients with schizophrenia: A multimodal proton magnetic resonance spectroscopy and functional …
J Kaminski, T Gleich, Y Fukuda, T Katthagen… - Biological …, 2020 - Elsevier
Background Cognitive deficits such as working memory (WM) impairment are core features
of schizophrenia. One candidate marker for the integrity of synaptic neurotransmission …
of schizophrenia. One candidate marker for the integrity of synaptic neurotransmission …
Neuroanatomical changes in people with high schizotypy: relationship to glutamate levels
G Modinos, A Egerton, A McLaughlin… - Psychological …, 2018 - cambridge.org
BackgroundCortical glutamatergic dysfunction is thought to be fundamental for psychosis
development, and may lead to structural degeneration through excitotoxicity. Glutamate …
development, and may lead to structural degeneration through excitotoxicity. Glutamate …