Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury

S Song, Z Xiao, FJ Dekker, GJ Poelarends… - Cellular and Molecular …, 2022 - Springer
The family of macrophage migration inhibitory factor (MIF) proteins in humans consist of MIF,
its functional homolog D-dopachrome tautomerase (D-DT, also known as MIF-2) and the …

2, 5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase

A Parkins, P Das, V Prahaladan, VM Rangel, L Xue… - Structure, 2023 - cell.com
Macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) are
two pleotropic cytokines, which are coexpressed in various cell types to activate the cell …

NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET

J van den Bor, ND Bergkamp, SM Anbuhl, F Dekker… - Cell Reports …, 2023 - cell.com
The therapeutic potential of ligands targeting disease-associated membrane proteins is
predicted by ligand-receptor binding constants, which can be determined using …

ACKR3 in olfactory glia cells shapes the immune defense of the olfactory mucosa

A Dietz, K Senf, EM Neuhaus - Glia, 2024 - Wiley Online Library
Barrier‐forming olfactory glia cells, termed sustentacular cells, play important roles for
immune defense of the olfactory mucosa, for example as entry sites for SARS‐CoV‐2 and …

Protective effect of Xixin–Ganjiang herb pair for warming the lungs to dissolve phlegm in chronic obstructive pulmonary disease rats based on integrated network …

P Huang, T Xiang, Q Wang, L Han… - Biomedical …, 2024 - Wiley Online Library
Xixin–Ganjiang herb pair (XGHP) is a classic combination for warming the lungs to dissolve
phlegm and is often used to treat a variety of chronic lung diseases; it can treat the syndrome …

[HTML][HTML] MIF, MMP-9 与慢性阻塞性肺疾病的研究进展

张海刚, 久太 - Advances in Clinical Medicine, 2022 - hanspub.org
慢性阻塞性肺疾病(COPD) 是一种全球高发的肺部疾病. 目前普遍认为慢性气道炎症和肺气肿是
COPD 主要疾病表现, 肺组织损伤与修复失衡是COPD 疾病进展的主要原因 …