A dominant area of antibody research is the extension of the use of this mighty experimental
and therapeutic tool for the specific detection of molecules for diagnostics, visualization, and …

The presence of Auger electrons (AE) among the decay products of a number of
radionuclides makes these radionuclides an attractive means for treating cancer because …

Gamma-ray emitting 111In, which is extensively used for imaging, is also a source of short-
range Auger electrons (AE). While exhibiting negligible effect outside cells, these AE …

This review describes artificial modular nanotransporters (MNTs) delivering their cargos into
target cells and then into the nuclei–the most vulnerable cell compartment for most …

Transcription factors (TFs) are at the center of the broad regulatory network orchestrating
gene expression programs that elicit different biological responses. For a long time, TFs …

Modular nanotransporters (MNTs) are multifunctional chimeric polypeptides for the multistep
transport of locally acting cytotoxic agents into the nuclei of cancer target cells. MNTs consist …

Abstract Targeted Meitner-Auger Therapy (TMAT) has potential for personalized treatment
thanks to its subcellular dosimetric selectivity, which is distinct from the dosimetry of β− and α …

Development of vehicles for the subcellular targeted delivery of biologically active agents is
very promising for the purposes of translational medicine. This review summarizes the …

Background The most attractive features of Auger electrons (AEs) in cancer therapy are their
extremely short range and sufficiently high linear energy transfer (LET) for a majority of them …

The distribution of modular nanotransporters (MNTs) that are used to deliver drugs into
melanoma cell nuclei after their intravenous administration into mice with Cloudman S91 …