Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of the blastocyst.
ESCs have two distinctive properties: ability to proliferate indefinitely, a feature referred as …

Stem cells represent an attractive resource for cardiac regeneration. However, the survival
and function of transplanted stem cells is poor and remains a major challenge for the …

Allogeneic islet transplantation allows for the re-establishment of glycemic control with the
possibility of insulin independence, but is severely limited by the scarcity of organ donors …

Stem cells hold promise in regenerative medicine due to their ability to proliferate and
differentiate into various cell types. However, their self-renewal and multipotency also raise …

Multiple strategies have been developed to efficiently differentiate human-induced
pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Here, we describe a protocol for …

The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and
holds great promise to advance regenerative medicine. iPSCs have the capacity for an …

Continuous loss of cardiomyocytes (CMs) is one of the fundamental characteristics of many
heart diseases, which eventually can lead to heart failure. Due to the limited proliferation …

Basic research on human pluripotent stem cell (hPSC)‐derived cardiomyocytes (CMs) for
cardiac regenerative therapy is one of the most active and complex fields to achieve this …

Pyroptosis, a programmed cell death marked by lytic and inflammatory characteristics, plays
a crucial role in non‑infectious inflammation‑related diseases but can lead to detrimental …

Separation of differentiated and undifferentiated cells without labeling is required for cell
analyses and clinical application of cultured differentiated cells in vitro. To proceed with the …