Vegetarian and vegan diets have increased worldwide in the last decades, according to the
knowledge that they might prevent coronary heart disease, cancer, and type 2 diabetes …

Background Vitamins B12 and folate participate in the one-carbon metabolism cycle and
hence regulate fetal growth. Though vitamin B12 deficiency is widely prevalent, the current …

Epidemiological studies have evaluated the association between maternal
methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase …

Background Methylenetetrahydrofolate reductase (MTHFR) is a critical enzyme in folate
metabolism and is involved in DNA methylation, DNA synthesis, and DNA repair. In addition …

Background: Whether a vegetarian diet is appropriate for pregnancy remains unclear.
Objective: This study aimed to determine the association between vegetarian diet during …

Objectives The methylenetetrahydrofolate dehydrogenase (MTHFD1) gene, as one of the
key genes involved in the folate pathway, has been reported to play a critical role in the …

Neural tube defect (NTD) is a severe congenital birth abnormalities involving incomplete
neural tube closure. 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene plays key …

Background and objective The MTHFR gene encodes the methylenetetrahydrofolate
reductase known to be involved in the homocysteine–methionine pathway. It has been …

Background Human studies of genetic risk factors for neural tube defects, severe birth
defects associated with long‐term health consequences in surviving children, have …

Background The 5, 10-methylenetetrahydrofolate reductase (MTHFR) and methionine
synthase (MS) are attractive candidates for screening for risk of neural tube defects (NTDs) …