Tissue-specific macrophages: how they develop and choreograph tissue biology
Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …
Human dendritic cell subsets: an update
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …
haematopoiesis that form an essential interface between the innate sensing of pathogens …
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
Understanding gene function and regulation in homeostasis and disease requires
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
knowledge of the cellular and tissue contexts in which genes are expressed. Here, we …
Monocyte conversion during inflammation and injury
Monocytes are circulating leukocytes important in both innate and adaptive immunity,
primarily functioning in immune defense, inflammation, and tissue remodeling. There are 2 …
primarily functioning in immune defense, inflammation, and tissue remodeling. There are 2 …
Tissue-specific immunity at the oral mucosal barrier
NM Moutsopoulos, JE Konkel - Trends in immunology, 2018 - cell.com
The oral mucosal barrier is constantly exposed to a plethora of triggers requiring immune
control, including a diverse commensal microbiome, ongoing damage from mastication, and …
control, including a diverse commensal microbiome, ongoing damage from mastication, and …
The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis
Macrophages provide a critical systemic network cells of the innate immune system.
Emerging data suggest that in addition, they have important tissue-specific functions that …
Emerging data suggest that in addition, they have important tissue-specific functions that …
Langerhans cells–the macrophage in dendritic cell clothing
T Doebel, B Voisin, K Nagao - Trends in immunology, 2017 - cell.com
Our assumptions on the identity and functions of Langerhans cells (LCs) of the epidermis
have undergone considerable changes. Once thought to be prototypic representatives of the …
have undergone considerable changes. Once thought to be prototypic representatives of the …
[HTML][HTML] Development of conventional dendritic cells: from common bone marrow progenitors to multiple subsets in peripheral tissues
Our understanding of conventional dendritic cell (cDC) development and the functional
specializations of distinct subsets in the peripheral tissues has increased greatly in recent …
specializations of distinct subsets in the peripheral tissues has increased greatly in recent …
A liver capsular network of monocyte-derived macrophages restricts hepatic dissemination of intraperitoneal bacteria by neutrophil recruitment
The liver is positioned at the interface between two routes traversed by pathogens in
disseminating infection. Whereas blood-borne pathogens are efficiently cleared in hepatic …
disseminating infection. Whereas blood-borne pathogens are efficiently cleared in hepatic …
Langerhans cells: sensing the environment in health and disease
J Deckers, H Hammad, E Hoste - Frontiers in immunology, 2018 - frontiersin.org
In the last few decades, our understanding of Langerhans cells (LCs) has drastically
changed based on novel findings regarding the developmental origin and biological …
changed based on novel findings regarding the developmental origin and biological …