Therapeutic strategies for enhancing angiogenesis in wound healing
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …
of years. The development of chronic, non-healing wounds is a persistent medical problem …
Engineering biomimetic materials for skeletal muscle repair and regeneration
KH Nakayama, M Shayan… - Advanced healthcare …, 2019 - Wiley Online Library
Although skeletal muscle is highly regenerative following injury or disease, endogenous self‐
regeneration is severely impaired in conditions of volume traumatic muscle loss …
regeneration is severely impaired in conditions of volume traumatic muscle loss …
Fibrin-based delivery strategies for acute and chronic wound healing
P Heher, S Mühleder, R Mittermayr, H Redl… - Advanced drug delivery …, 2018 - Elsevier
Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …
Fibrin glue as a drug delivery system
PP Spicer, AG Mikos - Journal of controlled release, 2010 - Elsevier
Fibrin glue has been used surgically for decades for hemostasis as well as a sealant. It has
also been researched as both a gel for cell delivery and a vehicle for drug delivery. The drug …
also been researched as both a gel for cell delivery and a vehicle for drug delivery. The drug …
Application of materials as medical devices with localized drug delivery capabilities for enhanced wound repair
The plentiful assortment of natural and synthetic materials can be leveraged to
accommodate diverse wound types, as well as different stages of the healing process. An …
accommodate diverse wound types, as well as different stages of the healing process. An …
Fibrin as a delivery system for therapeutic drugs and biomolecules
Fibrin is a natural biopolymer involved in the coagulation cascade. It acts as a reservoir for
growth factors, cells, and enzymes during wound healing and provides a scaffold for the …
growth factors, cells, and enzymes during wound healing and provides a scaffold for the …
Materials promoting viral gene delivery
K Kaygisiz, CV Synatschke - Biomaterials Science, 2020 - pubs.rsc.org
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
mutations by introducing new genetic information to cells either to correct a faulty gene or to …
Fibrin as a multipurpose physiological platform for bone tissue engineering and targeted delivery of bioactive compounds
B Bujoli, JC Scimeca, E Verron - Pharmaceutics, 2019 - mdpi.com
Although bone graft is still considered as the gold standard method, bone tissue engineering
offers promising alternatives designed to mimic the extracellular matrix (ECM) and to guide …
offers promising alternatives designed to mimic the extracellular matrix (ECM) and to guide …
Drug delivery systems for wound healing
NR Johnson, Y Wang - Current pharmaceutical biotechnology, 2015 - ingentaconnect.com
Protein, gene, and small molecule therapies hold great potential for facilitating
comprehensive tissue repair and regeneration. However, their clinical value will rely on …
comprehensive tissue repair and regeneration. However, their clinical value will rely on …
Fibrin hydrogels for non-viral vector delivery in vitro
Fibrin based hydrogels have been employed in vitro as a scaffold to promote tissue
formation and investigate underlying molecular mechanisms. These hydrogels support a …
formation and investigate underlying molecular mechanisms. These hydrogels support a …