Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Engineering biomimetic materials for skeletal muscle repair and regeneration

KH Nakayama, M Shayan… - Advanced healthcare …, 2019 - Wiley Online Library
Although skeletal muscle is highly regenerative following injury or disease, endogenous self‐
regeneration is severely impaired in conditions of volume traumatic muscle loss …

Fibrin-based delivery strategies for acute and chronic wound healing

P Heher, S Mühleder, R Mittermayr, H Redl… - Advanced drug delivery …, 2018 - Elsevier
Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

Fibrin glue as a drug delivery system

PP Spicer, AG Mikos - Journal of controlled release, 2010 - Elsevier
Fibrin glue has been used surgically for decades for hemostasis as well as a sealant. It has
also been researched as both a gel for cell delivery and a vehicle for drug delivery. The drug …

Application of materials as medical devices with localized drug delivery capabilities for enhanced wound repair

EJ Lee, BK Huh, SN Kim, JY Lee, CG Park… - Progress in materials …, 2017 - Elsevier
The plentiful assortment of natural and synthetic materials can be leveraged to
accommodate diverse wound types, as well as different stages of the healing process. An …

Fibrin as a delivery system for therapeutic drugs and biomolecules

A Breen, T O'Brien, A Pandit - Tissue Engineering Part B: Reviews, 2009 - liebertpub.com
Fibrin is a natural biopolymer involved in the coagulation cascade. It acts as a reservoir for
growth factors, cells, and enzymes during wound healing and provides a scaffold for the …

Materials promoting viral gene delivery

K Kaygisiz, CV Synatschke - Biomaterials Science, 2020 - pubs.rsc.org
Therapeutic viral gene delivery is an emerging technology which aims to correct genetic
mutations by introducing new genetic information to cells either to correct a faulty gene or to …

Fibrin as a multipurpose physiological platform for bone tissue engineering and targeted delivery of bioactive compounds

B Bujoli, JC Scimeca, E Verron - Pharmaceutics, 2019 - mdpi.com
Although bone graft is still considered as the gold standard method, bone tissue engineering
offers promising alternatives designed to mimic the extracellular matrix (ECM) and to guide …

Drug delivery systems for wound healing

NR Johnson, Y Wang - Current pharmaceutical biotechnology, 2015 - ingentaconnect.com
Protein, gene, and small molecule therapies hold great potential for facilitating
comprehensive tissue repair and regeneration. However, their clinical value will rely on …

Fibrin hydrogels for non-viral vector delivery in vitro

A des Rieux, A Shikanov, LD Shea - Journal of Controlled Release, 2009 - Elsevier
Fibrin based hydrogels have been employed in vitro as a scaffold to promote tissue
formation and investigate underlying molecular mechanisms. These hydrogels support a …