Alzheimer's disease remains incurable, and the failures of current disease-modifying
strategies for Alzheimer's disease could be attributed to a lack of in vivo models that …

The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …

Background Although many therapeutic strategies for Alzheimer's disease (AD) have been
explored, these strategies are seldom used in the clinic. Therefore, AD therapeutic research …

The accumulation of hyperphosphorylated tau protein aggregates is a key pathogenic event
in Alzheimer's disease (AD) and induces mitochondrial dysfunction and reactive oxygen …

Marine biosphere is the largest one of the earth and harbors an enormous number of
different organisms. Living conditions differ fundamentally from those in terrestrial …

Alzheimer's disease (AD) is a common age-related neurodegenerative disease
characterized by progressive cognitive decline and irreversible memory impairment …

Alzheimer's disease (AD) is characterized by amyloid (A) β peptide accumulation and
intracellular neurofibrillary tangles. New hypotheses have suggested that AD involves …

Marine phycotoxins are a multiplicity of bioactive compounds which are produced by
microalgae and bioaccumulate in the marine food web. Phycotoxins affect the ecosystem …

Stem cells have emerged as a potential therapy for a range of neural insults, but their
application in Alzheimer's disease (AD) is still limited and the mechanisms underlying the …

Patients recovering from sepsis have higher rates of CNS morbidities associated with long-
lasting impairment of cognitive functions, including neurodegenerative diseases. However …