Recent developments on the potential biological applications of transition metal complexes of thiosemicarbazone derivatives

V Singh, VNV Palakkeezhillam, V Manakkadan… - Polyhedron, 2023 - Elsevier
This review talks about the synthesis, and coordination chemistry of thiosemicarbazone and
its bonding with transition metals like copper, nickel, zinc, palladium, and ruthenium and …

Transition metal complexes of thiosemicarbazides, thiocarbohydrazides, and their corresponding carbazones with Cu (I), Cu (II), Co (II), Ni (II), Pd (II), and Ag (I)—A …

AA Aly, EM Abdallah, SA Ahmed, MM Rabee, S Bräse - Molecules, 2023 - mdpi.com
This review focuses on some interesting and recent applications of transition metals towards
the complexation of thiosemicarbazides, thiocarbohydrazides, and their corresponding …

Synthesis, characterization, thermal properties, antimicrobial evaluation, ADMET study, and molecular docking simulation of new mono Cu (II) and Zn (II) complexes …

A Ragab, YA Ammar, A Ezzat, AM Mahmoud… - Computers in Biology …, 2022 - Elsevier
One of the interesting research fields is developing and assessing novel metal-containing
medications. A new isatin-3-thiosemicarbazone derivative 4 was synthesized by two …

Biological investigation of N-methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors

I D'Agostino, GE Mathew, P Angelini… - Journal of Enzyme …, 2022 - Taylor & Francis
The enormous burden of the COVID-19 pandemic in economic and healthcare terms has
cast a shadow on the serious threat of antimicrobial resistance, increasing the inappropriate …

Sensor properties of thiosemicarbazones in different analytical methods

O Özbek, C Berkel - Polyhedron, 2023 - Elsevier
Thiosemicarbazone derivatives are compounds generally obtained from the condensation
reaction of thiosemicarbazide with aldehydes and ketones. These molecules have gained a …

Exploring the anticancer potential of thiadiazole derivatives of substituted thiosemicarbazones formed via copper‐mediated cyclization

VN Vadakkedathu Palakkeezhillam… - Applied …, 2023 - Wiley Online Library
A couple of N‐(4)‐morpholine/pyrrolidine‐substituted thiosemicarbazones (TSCs) of
fluorene‐2‐carboxaldehyde (FM and FP), and their corresponding thiadiazoles (TDZs)(CFM …

New Coumarin− Thiosemicarbazone Based Zn (II), Ni (II) and Co (II) Metal Complexes: Investigation of Cholinesterase, α‐Amylase, and α‐Glucosidase Enzyme …

E Çelik, M Özdemir, B Köksoy, T Taskin‐Tok… - …, 2023 - Wiley Online Library
New coumarin− thiosemicarbazone compounds and their zinc (II), nickel (II), and copper (II)
metal complexes were synthesized and characterized. The inhibitory activities of these new …

Selective metal chelation by a thiosemicarbazone derivative interferes with mitochondrial respiration and ribosome biogenesis in Candida albicans

X Duan, Z Xie, L Ma, X Jin, M Zhang, Y Xu… - Microbiology …, 2022 - Am Soc Microbiol
Metal chelation is generally considered as a promising antifungal approach but its specific
mechanisms are unclear. Here, we identify 13 thiosemicarbazone derivatives that exert …

Single crystal X-ray diffraction analysis, spectroscopic measurement, quantum chemical studies, antimicrobial potency and molecular docking of a new [Co (NCS) 4] 2 …

C Gharbi, H Louis, B Essghaier, CB Ubah… - Journal of Molecular …, 2024 - Elsevier
A new cobalt (II) complex was synthesized and characterized by physicochemical
evidences. According to crystallography study, the molecular structure consisting of anionic …

Coordination behavior of Schiff base copper complexes and structural characterization

M Kumar, C Mohan, S Kumar, K Epifantsev, V Singh… - MRS Advances, 2022 - Springer
Herein, we report the coordination behavior of 2-Acetyl thiophene thiosemicarbazone with
copper chloride at various pH. Three copper complexes,[Cu (C7H9N3S2) 2Cl2] Cl2,[Cu …