Role of oxidative stress and inflammation-related signaling pathways in doxorubicin-induced cardiomyopathy
S Shi, Y Chen, Z Luo, G Nie, Y Dai - Cell Communication and Signaling, 2023 - Springer
Doxorubicin (DOX) is a powerful and commonly used chemotherapeutic drug, used alone or
in combination in a variety of cancers, while it has been found to cause serious cardiac side …
in combination in a variety of cancers, while it has been found to cause serious cardiac side …
Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases
Z Chen, W Ding, X Yang, T Lu, Y Liu - Journal of ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …
Nrf2: a dark horse in doxorubicin-induced cardiotoxicity
X Zhao, Z Tian, M Sun, D Dong - Cell death discovery, 2023 - nature.com
Being a broad-spectrum anticancer drug, doxorubicin is indispensable for clinical treatment.
Unexpectedly, its cardiotoxic side effects have proven to be a formidable obstacle …
Unexpectedly, its cardiotoxic side effects have proven to be a formidable obstacle …
Protective effect of berberine against LPS-induced injury in the intestine: a review
F Izadparast, B Riahi-Zajani, F Yarmohammadi… - Cell Cycle, 2022 - Taylor & Francis
Sepsis is a systemic inflammatory condition caused by an unbalanced immunological
response to infection, which affects numerous organs, including the intestines …
response to infection, which affects numerous organs, including the intestines …
[HTML][HTML] Melatonin alleviates doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, pyroptosis and apoptosis by activating Sirt1/Nrf2 pathway
W Zhang, X Wang, Y Tang, C Huang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Melatonin confers cardioprotective effects on multiple cardiovascular diseases, including
doxorubicin-induced cardiomyopathy. The effectiveness of melatonin in mitigating …
doxorubicin-induced cardiomyopathy. The effectiveness of melatonin in mitigating …
Boesenbergia rotunda displayed anti-inflammatory, antioxidant and anti-apoptotic efficacy in doxorubicin‐induced cardiotoxicity in rats
L Zhang, Q Jiang, X Wang, A Jaisi, OJ Olatunji - Scientific Reports, 2023 - nature.com
This study evaluated the cardioprotective properties of Boesenbergia rotunda extract (BrE)
against doxorubicin (DOX) induced cardiotoxicity. Rats received oral gavage of BrE for 28 …
against doxorubicin (DOX) induced cardiotoxicity. Rats received oral gavage of BrE for 28 …
Wei-Tong-Xin ameliorates functional dyspepsia via inactivating TLR4/MyD88 by regulating gut microbial structure and metabolites
X Zhang, W Liu, S Zhang, J Wang, X Yang, R Wang… - Phytomedicine, 2022 - Elsevier
Abstract Background Wei-Tong-Xin (WTX) is a traditional Chinese medicine (TCM) that has
been screened and improved in accordance with the famous ancient Chinese formula" Wan …
been screened and improved in accordance with the famous ancient Chinese formula" Wan …
Polyguluronic acid alleviates doxorubicin-induced cardiotoxicity by suppressing Peli1-NLRP3 inflammasome-mediated pyroptosis
E Zhang, C Shang, M Ma, X Zhang, Y Liu, S Song… - Carbohydrate …, 2023 - Elsevier
Polyguluronic acid (PG), a polysaccharide from alginate, possesses excellent bioactivities.
We prepared high-purity PG with 10.41 kDa molecular weight (Mw) and a 59 average …
We prepared high-purity PG with 10.41 kDa molecular weight (Mw) and a 59 average …
Spinacetin alleviates doxorubicin-induced cardiotoxicity by initiating protective autophagy through SIRT3/AMPK/mTOR pathways
D Liu, L Zhao - Phytomedicine, 2022 - Elsevier
Background Doxorubicin-induced myocardiopathy is a massive obstacle in administering
chemotherapeutic drugs in cancer patients. Purposes In the present study, we aim to …
chemotherapeutic drugs in cancer patients. Purposes In the present study, we aim to …
Mechanisms of arsenic exposure-induced hypertension and atherosclerosis: an updated overview
S Balarastaghi, R Rezaee, AW Hayes… - … Trace Element Research, 2023 - Springer
Arsenic is an abundant element in the earth's crust. In the environment and within the human
body, this toxic element can be found in both organic and inorganic forms. Chronic exposure …
body, this toxic element can be found in both organic and inorganic forms. Chronic exposure …