Andrographolide and its derivatives: Current achievements and future perspectives
H Zhang, S Li, Y Si, H Xu - European Journal of Medicinal Chemistry, 2021 - Elsevier
Natural product andrographolide isolated from the plant Andrographis paniculata shows a
plethora of biological activities, including anti-tumor, anti-bacterial, anti-inflammation, anti …
plethora of biological activities, including anti-tumor, anti-bacterial, anti-inflammation, anti …
The potential role of plant secondary metabolites on antifungal and immunomodulatory effect
X Zhou, M Zeng, F Huang, G Qin, Z Song… - Applied Microbiology and …, 2023 - Springer
With the widespread use of antibiotic drugs worldwide and the global increase in the
number of immunodeficient patients, fungal infections have become a serious threat to …
number of immunodeficient patients, fungal infections have become a serious threat to …
[HTML][HTML] A polypyrrole/GO/ZnO nanocomposite modified pencil graphite electrode for the determination of andrographolide in aqueous samples
RT Hussain, AKMS Islam, M Khairuddean… - Alexandria Engineering …, 2022 - Elsevier
This paper presents a novel electrochemical sensor based on a pencil graphite electrode
(PGE) modified with molecularly imprinted graphene oxide/zinc oxide nanocomposites for a …
(PGE) modified with molecularly imprinted graphene oxide/zinc oxide nanocomposites for a …
Natural compound glycyrrhetinic acid protects against doxorubicin-induced cardiotoxicity by activating the Nrf2/HO-1 signaling pathway
Y Cheng, X Wu, X Nie, Y Wu, C Zhang, SMY Lee, K Lv… - Phytomedicine, 2022 - Elsevier
Background As one of the most classic antineoplastic agents, doxorubicin (Dox) is
extensively used to treat a wide range of cancers. Nevertheless, the clinical outcomes of Dox …
extensively used to treat a wide range of cancers. Nevertheless, the clinical outcomes of Dox …
Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor
J Shi, J Li, J Li, R Li, X Wu, F Gao, L Zou, WWS Mak… - Phytomedicine, 2021 - Elsevier
Background Therapeutic regimens of breast cancer treatment are increasingly inclined to
adopt combination strategy based on the broad spectrum antitumor effect of doxorubicin …
adopt combination strategy based on the broad spectrum antitumor effect of doxorubicin …
Anti-cancer agent: the labdane diterpenoid-andrographolide
In spite of the progress in treatment strategies, cancer remains a major cause of death
worldwide. Therefore, the main challenge should be the early diagnosis of cancer and the …
worldwide. Therefore, the main challenge should be the early diagnosis of cancer and the …
[Retracted] Protective Effects of Amauroderma rugosum on Doxorubicin‐Induced Cardiotoxicity through Suppressing Oxidative Stress, Mitochondrial Dysfunction …
J Li, Y Cheng, R Li, X Wu, C Zheng… - Oxidative Medicine …, 2022 - Wiley Online Library
Clinical outcomes for doxorubicin (Dox) are limited by its cardiotoxicity but a combination of
Dox and agents with cardioprotective activities is an effective strategy to improve its …
Dox and agents with cardioprotective activities is an effective strategy to improve its …
[HTML][HTML] Garcinone E triggers apoptosis and cell cycle arrest in human colorectal cancer cells by mediating a reactive oxygen species–dependent JNK signaling …
R Li, C Zheng, PHT Shiu, P Rangsinth, W Wang… - Biomedicine & …, 2023 - Elsevier
Despite various therapeutic approaches, colorectal cancer is among the most fatal diseases
globally. Hence, developing novel and more effective methods for colorectal cancer …
globally. Hence, developing novel and more effective methods for colorectal cancer …
The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway
Z Liu, X Wu, K Dai, R Li, J Zhang, D Sheng, SMY Lee… - Phytomedicine, 2022 - Elsevier
Background: The anti-cancer activity of andrographolide (Andro) has been extensively
demonstrated in recent years. It is supposed that modifying the chemical structure of Andro …
demonstrated in recent years. It is supposed that modifying the chemical structure of Andro …
Reshaping tumor blood vessels to enhance drug penetration with a multistrategy synergistic nanosystem
Y Li, Y Liu, B Du, G Cheng - Molecular Pharmaceutics, 2020 - ACS Publications
Due to the abnormal tumor vasculature and dense stroma, there is limited tumor perfusion in
the immunosuppressive tumor microenvironment (TME). In order to reshape tumor blood …
the immunosuppressive tumor microenvironment (TME). In order to reshape tumor blood …