A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …

In the initiation or exacerbation of Alzheimer disease, the dissemination of oral
microorganisms into the brain tissue or the low‐level systemic inflammation have been …

Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and
causes destructive and irreversible cognitive decline. Failures in the development of …

Abstract Toll-like receptor 4 (TLR4) signaling in the brain mediates autoimmune responses
and induces neuroinflammation that results in neurodegenerative diseases, such as …

More than 300 years ago, Antony van Leewenhoeck first described observing single-celled
microorganisms, which he termed “animalcules,” examining his saliva under a microscope …

Since the inception of the human microbiome project (HMP) by the US National Institutes of
Health (NIH) in 2007 there has been a keen resurgence in our recognition of the human …

Neuroinflammation is initiated by activation of the brain's innate immune system in response
to an inflammatory challenge. Insufficient control of neuroinflammation leads to enhanced or …

Background Neuroinflammation is an underlying pathology of all neurological conditions,
the understanding of which is still being comprehended. A specific molecular pathway that …

The importance of glycosylation (post-translational attachment of glycan residues to
proteins) in the context of neuroinflammation is only now beginning to be understood …

This study examined the protective effect of 6‐Gingerol (6G) against lipopolysaccharide
(LPS)‐induced cognitive impairments, oxidative stress, neuroplasticity, amyloidogenesis …