Enabling technology and core theory of synthetic biology
Synthetic biology provides a new paradigm for life science research (“build to learn”) and
opens the future journey of biotechnology (“build to use”). Here, we discuss advances of …
opens the future journey of biotechnology (“build to use”). Here, we discuss advances of …
Synthetic yeast genomes for studying chromosomal features
De novo synthesis of a genome makes it possible to probe fundamental biological questions
that are experimentally inaccessible with traditional approaches. For example, the functions …
that are experimentally inaccessible with traditional approaches. For example, the functions …
Efficient de novo assembly and modification of large DNA fragments
S Jiang, Y Tang, L Xiang, X Zhu, Z Cai, L Li… - Science China Life …, 2022 - Springer
Synthetic genomics has provided new bottom-up platforms for the functional study of viral
and microbial genomes. The construction of the large, gigabase (Gb)-sized genomes of …
and microbial genomes. The construction of the large, gigabase (Gb)-sized genomes of …
An Omic's data-driven approach towards engineering mammalian cell factories and bioprocesses for biopharmaceutical Production
M Torres, V Ortuzar, AJ Dickson, H Hussain - Cell Culture Engineering and …, 2022 - Springer
In the last decade, biopharmaceutical production in mammalian systems has experienced
significant advances in product titres and quality, reaching multi-gram per litre bioprocesses …
significant advances in product titres and quality, reaching multi-gram per litre bioprocesses …
Artificial chromosomes
D Fachinetti, H Masumoto, N Kouprina - Experimental Cell Research, 2020 - Elsevier
Forty years have gone by since Clark & Carbon [1] cloned the first functional eukaryotic
centromere DNA from budding yeast. A short centromere DNA segment, which was later …
centromere DNA from budding yeast. A short centromere DNA segment, which was later …