Nicotine and the renin-angiotensin system

JM Oakes, RM Fuchs, JD Gardner… - American Journal …, 2018 - journals.physiology.org
Cigarette smoking is the single most important risk factor for the development of
cardiovascular and pulmonary diseases (CVPD). Although cigarette smoking has been in …

Association of smoking history with severe and critical outcomes in COVID-19 patients: a systemic review and meta-analysis

H Zhang, S Ma, T Han, G Qu, C Cheng, JP Uy… - European journal of …, 2021 - Elsevier
Introduction The highly infectious coronavirus disease 2019 (COVID-19) has now rapidly
spread around the world. This meta-analysis was strictly focused on the influence of …

Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract

JC Smith, EL Sausville, V Girish, ML Yuan… - Developmental cell, 2020 - cell.com
The factors mediating fatal SARS-CoV-2 infections are poorly understood. Here, we show
that cigarette smoke causes a dose-dependent upregulation of angiotensin converting …

Does COVID19 infect the brain? If so, smokers might be at a higher risk

N Kabbani, JL Olds - Molecular pharmacology, 2020 - ASPET
COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now
the United States. While the majority of infected cases appear mild, in some cases …

Implications for neuromodulation therapy to control inflammation and related organ dysfunction in COVID-19

M Fudim, YJ Qadri, K Ghadimi, DB MacLeod… - Journal of …, 2020 - Springer
COVID-19 is a syndrome that includes more than just isolated respiratory disease, as severe
acute respiratory syndrome–coronavirus 2 (SARS-CoV2) also interacts with the …

Severe acute respiratory syndrome coronavirus 2 infection reaches the human nervous system: How?

VN Uversky, F Elrashdy, A Aljadawi… - Journal of …, 2021 - Wiley Online Library
Without protective and/or therapeutic agents the severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) infection known as coronavirus disease 2019 is quickly …

Prevalence and patterns of symptoms of dysautonomia in patients with long‐COVID syndrome: a cross‐sectional study

AM Eldokla, AA Mohamed‐Hussein… - Annals of Clinical …, 2022 - Wiley Online Library
Background The association between autonomic dysfunction and long‐COVID syndrome is
established. However, the prevalence and patterns of symptoms of dysautonomia in long …

Nicotine and the nicotinic cholinergic system in COVID‐19

Y Tizabi, B Getachew, RL Copeland… - The FEBS …, 2020 - Wiley Online Library
There is an urgent need to address the devastating pandemic, COVID‐19, caused by SARS‐
CoV‐2. The efforts to understand the details of this disease in hope of providing effective …

COVID‐19 breakthroughs: separating fact from fiction

P Dhillon, M Breuer, N Hirst - The FEBS journal, 2020 - Wiley Online Library
The newly recognised coronavirus SARS‐CoV‐2, causative agent of coronavirus disease
(COVID‐19), has caused a pandemic with huge ramifications for human interactions around …

COVID-19, COPD, and AECOPD: immunological, epidemiological, and clinical aspects

F Polverino, F Kheradmand - Frontiers in Medicine, 2021 - frontiersin.org
The newly identified severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2)
causes several heterogeneous clinical conditions collectively known as Coronavirus …