MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Abstract The microRNA (miR) 183 cluster, which is comprised of miRs-183,-96 and-182, is
also a miR family with sequence homology. Despite the strong similarity in the sequences of …

Abstract Rationale: Long extracellular RNAs (exRNAs) in plasma can be profiled by new
sequencing technologies, even with low abundance. However, cancer-related exRNAs and …

MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …

Abstract microRNAs (miRNAs) are small non-coding RNAs that control gene expression
posttranscriptionally and are part of the giant non codifying genoma. Cumulating data …

The process of DNA CpG methylation has been extensively investigated for over 50 years
and revealed associations between changing methylation status of CpG islands and gene …

Background: In this paper, the utility of urine-circulating microRNAs (miRNAs) as the
potential biomarker of prostate cancer (PCa), the second most prevalent male cancer …

Alzheimer's disease (AD) is the most common type of age-related neurodegenerative
disorder; nevertheless, nowadays there are no reliable biomarkers or non-invasive …

Metastatic castration resistant prostate cancer (mCRPC) is associated with high mortality,
where monitoring of disease activity is still a major clinical challenge. The role of microRNAs …

Elevated levels of miR-21 expression are associated with many cancers, suggesting it may
be a promising clinical biomarker. In prostate cancer (PCa), however, there is still no …