Atopic dermatitis: Role of the skin barrier, environment, microbiome, and therapeutic agents

T Luger, M Amagai, B Dreno, MA Dagnelie… - Journal of …, 2021 - Elsevier
Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by eczematous
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …

Epicutaneous sensitization in the development of food allergy: what is the evidence and how can this be prevented?

HA Brough, KC Nadeau, SB Sindher, SS Alkotob… - Allergy, 2020 - Wiley Online Library
There is increasing evidence regarding the importance of allergic sensitization through the
skin. In this review, we provide an overview of the atopic march and immune mechanism …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Recent developments and highlights in allergic rhinitis

Y Meng, C Wang, L Zhang - Allergy, 2019 - Wiley Online Library
Allergic rhinitis (AR) is a disease with high prevalence all over the world and therefore
needs to be thoroughly investigated and treated accordingly. The mechanisms underlying …

Regulatory immune mechanisms in tolerance to food allergy

P Satitsuksanoa, K Jansen, A Głobińska… - Frontiers in …, 2018 - frontiersin.org
Oral tolerance can develop after frequent exposure to food allergens. Upon ingestion, food
is digested into small protein fragments in the gastrointestinal tract. Small food particles are …

Recent developments and highlights in food allergy

T Eiwegger, L Hung, KE San Diego, L O'Mahony… - Allergy, 2019 - Wiley Online Library
The achievement of long‐lasting, safe treatments for food allergy is dependent on the
understanding of the immunological basis of food allergy. Accurate diagnosis is essential for …

Recent developments and highlights in biomarkers in allergic diseases and asthma

I Eguiluz‐Gracia, TR Tay, M Hew, MM Escribese… - Allergy, 2018 - Wiley Online Library
The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

[PDF][PDF] Mechanisms by which atopic dermatitis predisposes to food allergy and the atopic march

EH Tham, DYM Leung - Allergy, asthma & immunology …, 2018 - synapse.koreamed.org
The Atopic march denotes the progression from atopic dermatitis (AD) to the development of
other allergic disorders such as immunoglobulin (Ig) E-mediated food allergy, allergic rhinitis …

Current insights into the genetics of food allergy

K Kanchan, S Clay, H Irizar, S Bunyavanich… - Journal of Allergy and …, 2021 - Elsevier
Food allergy (FA), a growing public health burden in the United States, and familial
aggregation studies support strong roles for both genes and environment in FA risk …

Inborn errors of immunity manifesting as atopic disorders

M Vaseghi-Shanjani, KL Smith, RJ Sara… - Journal of Allergy and …, 2021 - Elsevier
Inborn errors of immunity are traditionally best known for enhancing susceptibility to
infections. However, allergic inflammation, among other types of immune dysregulation …