Monoaminergic neuropathology in Alzheimer's disease
None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …
patterns of the neuropathological changes at the cellular and regional levels, and their …
[HTML][HTML] Lewy bodies, iron, inflammation and neuromelanin: pathological aspects underlying Parkinson's disease
P Riederer, T Nagatsu, MBH Youdim, M Wulf… - Journal of Neural …, 2023 - Springer
Since the description of some peculiar symptoms by James Parkinson in 1817, attempts
have been made to define its cause or at least to enlighten the pathology of “Parkinson's …
have been made to define its cause or at least to enlighten the pathology of “Parkinson's …
[HTML][HTML] Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology
S Liu, M Fan, JX Xu, LJ Yang, CC Qi, QR Xia… - Journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …
Type 2 diabetes, cognition, and dementia in older adults: toward a precision health approach
B Cholerton, LD Baker, TJ Montine… - Diabetes Spectrum, 2016 - Am Diabetes Assoc
IN BRIEF There has been a concurrent dramatic rise in type 2 diabetes and dementia in the
United States, and type 2 diabetes shares common genetic and environmental risk factors …
United States, and type 2 diabetes shares common genetic and environmental risk factors …
Intracerebroventricular streptozotocin as a model of Alzheimer's disease: neurochemical and behavioral characterization in mice
KG Ravelli, BA Rosário, R Camarini… - Neurotoxicity …, 2017 - Springer
Streptozotocin has been widely used to mimic some aspects of Alzheimer's disease (AD).
However, especially in mice, several characteristics involved in the streptozotocin (STZ) …
However, especially in mice, several characteristics involved in the streptozotocin (STZ) …
Intranasal metformin treatment ameliorates cognitive functions via insulin signaling pathway in ICV-STZ-induced mice model of Alzheimer's disease
Aims The relationship between type 2 diabetes and Alzheimer's disease (AD) provides
evidence that insulin and insulin sensitizers may be beneficial for the treatment of AD. The …
evidence that insulin and insulin sensitizers may be beneficial for the treatment of AD. The …
The diabetic brain and cognition
P Riederer, AD Korczyn, SS Ali, O Bajenaru… - Journal of neural …, 2017 - Springer
The prevalence of both Alzheimer's disease (AD) and vascular dementia (VaD) is increasing
with the aging of the population. Studies from the last several years have shown that people …
with the aging of the population. Studies from the last several years have shown that people …
Anthocyanins as a potential pharmacological agent to manage memory deficit, oxidative stress and alterations in ion pump activity induced by experimental sporadic …
SM Pacheco, MSP Soares, JM Gutierres… - The Journal of …, 2018 - Elsevier
Anthocyanins (ANT) are polyphenolic flavonoids with antioxidant and neuroprotective
properties. This study evaluated the effect of ANT treatment on cognitive performance and …
properties. This study evaluated the effect of ANT treatment on cognitive performance and …
Animal model of Alzheimer's disease induced by streptozotocin: New insights about cholinergic pathway
SSL Silva, LV Tureck, LC Souza, JV Mello-Hortega… - Brain research, 2023 - Elsevier
Alzheimer's disease (AD) is of multifactorial origin, and still presents several gaps regarding
its development and progression. Disorders of the cholinergic system are well known to be …
its development and progression. Disorders of the cholinergic system are well known to be …
Evidence of disturbed insulin signaling in animal models of Alzheimer's disease
Since glucose reuptake by neurons is mostly independent of insulin, it has been an
intriguing question whether insulin has or not any roles in the brain. Consequently, the …
intriguing question whether insulin has or not any roles in the brain. Consequently, the …