Virulence factors of the Mycobacterium tuberculosis complex
MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …
Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity
The pe/ppe genes represent one of the most intriguing aspects of the M ycobacterium
tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …
tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …
Latent tuberculosis infection: myths, models, and molecular mechanisms
NK Dutta, PC Karakousis - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
The aim of this review is to present the current state of knowledge on human latent
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …
tuberculosis infection (LTBI) based on clinical studies and observations, as well as …
Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers
Tuberculosis (TB) is primarily associated with decline in immune health status. As gut
microbiome (GM) is implicated in the regulation of host immunity and metabolism, here we …
microbiome (GM) is implicated in the regulation of host immunity and metabolism, here we …
Non-tuberculous mycobacteria: Molecular and physiological bases of virulence and adaptation to ecological niches
Non-tuberculous mycobacteria (NTM) are paradigmatic colonizers of the total environment,
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …
DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis
SS Shell, EG Prestwich, SH Baek, RR Shah… - PLoS …, 2013 - journals.plos.org
DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA
methylation is associated with gene repression, while it exerts both activating and repressive …
methylation is associated with gene repression, while it exerts both activating and repressive …
Widespread suppression of intragenic transcription initiation by H-NS
SS Singh, N Singh, RP Bonocora… - Genes & …, 2014 - genesdev.cshlp.org
Widespread intragenic transcription initiation has been observed in many species. Here we
show that the Escherichia coli ehxCABD operon contains numerous intragenic promoters in …
show that the Escherichia coli ehxCABD operon contains numerous intragenic promoters in …
The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance
J Burian, S Ramón-García, G Sweet… - Journal of Biological …, 2012 - ASBMB
Intrinsic drug resistance in Mycobacterium tuberculosis limits therapeutic options for treating
tuberculosis. The mycobacterial transcriptional regulator whiB7 contributes to intrinsic …
tuberculosis. The mycobacterial transcriptional regulator whiB7 contributes to intrinsic …
New approaches and therapeutic options for Mycobacterium tuberculosis in a dormant state
We are far away from the days when tuberculosis (TB) accounted for 1 in 4 deaths during the
19th century. However, Mycobacterium tuberculosis complex (MTBC) strains are still the …
19th century. However, Mycobacterium tuberculosis complex (MTBC) strains are still the …
Sigma factors and promoters in Corynebacterium glutamicum
M Pátek, J Nešvera - Journal of biotechnology, 2011 - Elsevier
The Corynebacterium glutamicum genome codes for 7 sigma subunits (factors) of RNA
polymerase (RNAP): primary sigma factor SigA (σA), primary-like SigB and 5 other …
polymerase (RNAP): primary sigma factor SigA (σA), primary-like SigB and 5 other …