Biological Aging Acceleration Due to Environmental Exposures: An Exciting New Direction in Toxicogenomics Research

S Dutta, JM Goodrich, DC Dolinoy, DM Ruden - Genes, 2023 - mdpi.com
Biological clock technologies are designed to assess the acceleration of biological age (B-
age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to …

Association between indoor PM2. 5 components and accelerated biological aging in schizophrenia patients: Evidence from multi-omics mechanisms

R Pan, XX Yi, Y Xu, J Song, W Yi, J Liu, R Song… - Journal of Hazardous …, 2024 - Elsevier
Indoor fine particulate matter (PM 2.5) poses a considerable hazard to the aging process,
particularly in vulnerable populations such as schizophrenia patients who frequently spend …

[HTML][HTML] Associations of prenatal one-carbon metabolism nutrients and metals with epigenetic aging biomarkers at birth and in childhood in a US cohort

AK Bozack, SL Rifas-Shiman, AA Baccarelli… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Epigenetic gestational age acceleration (EGAA) at birth and epigenetic age acceleration
(EAA) in childhood may be biomarkers of the intrauterine environment. We investigated the …

Prenatal and childhood lead exposure is prospectively associated with biological markers of aging in adolescence

OM Halabicky, MM Téllez-Rojo, JM Goodrich… - Science of The Total …, 2024 - Elsevier
Few studies have related early life lead exposure to adolescent biological aging, a period
characterized by marked increases in maturational tempo. We examined associations …

Threshold and combined effects of heavy metals on the risk of phenotypic age acceleration among US adults

Y Liu, Z Jin, S Fu - BioMetals, 2024 - Springer
Accumulation of heavy metals in the body has been shown to affect the phenotypic age
(PhenoAge). However, the combined and threshold effects of blood heavy metals on the risk …