Mitochondrial fusion, fission, and mitochondrial toxicity
Mitochondrial dynamics are regulated by two sets of opposed processes: mitochondrial
fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as …
fusion and fission, and mitochondrial biogenesis and degradation (including mitophagy), as …
Melatonin: a mitochondrial targeting molecule involving mitochondrial protection and dynamics
Melatonin has been speculated to be mainly synthesized by mitochondria. This speculation
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
is supported by the recent discovery that aralkylamine N-acetyltransferase/serotonin N …
Pineal calcification, melatonin production, aging, associated health consequences and rejuvenation of the pineal gland
The pineal gland is a unique organ that synthesizes melatonin as the signaling molecule of
natural photoperiodic environment and as a potent neuronal protective antioxidant. An intact …
natural photoperiodic environment and as a potent neuronal protective antioxidant. An intact …
Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy
Acute myocardial infarction (MI) is a major cause of mortality and disability worldwide. In
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …
The main molecular mechanisms underlying methamphetamine-induced neurotoxicity and implications for pharmacological treatment
X Yang, Y Wang, Q Li, Y Zhong, L Chen… - Frontiers in molecular …, 2018 - frontiersin.org
Methamphetamine (METH) is a popular new-type psychostimulant drug with complicated
neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the …
neurotoxicity. In spite of mounting evidence on METH-induced damage of neural cell, the …
Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms
Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …
Increasing Nrf2 activity as a treatment approach in neuropsychiatry
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by NFE2L2.
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …
Melatonin and mitochondrial function during ischemia/reperfusion injury
Z Ma, Z Xin, W Di, X Yan, X Li, RJ Reiter… - Cellular and Molecular …, 2017 - Springer
Ischemia/reperfusion (IR) injury occurs in many organs and tissues, and contributes to
morbidity and mortality worldwide. Melatonin, an endogenously produced indolamine …
morbidity and mortality worldwide. Melatonin, an endogenously produced indolamine …
[HTML][HTML] Mitochondrial dysfunction: A fatal blow in depression
Y Song, H Cao, C Zuo, Z Gu, Y Huang, J Miao… - Biomedicine & …, 2023 - Elsevier
Mitochondria maintain the normal physiological function of nerve cells by producing
sufficient cellular energy and performing crucial roles in maintaining the metabolic balance …
sufficient cellular energy and performing crucial roles in maintaining the metabolic balance …
Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium‐dependent translocation of Drp1 to the …
S Xu, H Pi, L Zhang, N Zhang, YM Li… - Journal of pineal …, 2016 - Wiley Online Library
Cadmium (Cd) is a persistent environmental toxin and occupational pollutant that is
considered to be a potential risk factor in the development of neurodegenerative diseases …
considered to be a potential risk factor in the development of neurodegenerative diseases …