Wearable microneedle-based electrochemical aptamer biosensing for precision dosing of drugs with narrow therapeutic windows

S Lin, X Cheng, J Zhu, B Wang, D Jelinek, Y Zhao… - Science …, 2022 - science.org
Therapeutic drug monitoring is essential for dosing pharmaceuticals with narrow therapeutic
windows. Nevertheless, standard methods are imprecise and involve invasive/resource …

[HTML][HTML] Impedimetric sensing: an emerging tool for combating the COVID-19 pandemic

V Ong, A Soleimani, F Amirghasemi, S Khazaee Nejad… - Biosensors, 2023 - mdpi.com
The COVID-19 pandemic revealed a pressing need for the development of sensitive and low-
cost point-of-care sensors for disease diagnosis. The current standard of care for COVID-19 …

Microneedle aptamer-based sensors for continuous, real-time therapeutic drug monitoring

Y Wu, F Tehrani, H Teymourian, J Mack… - Analytical …, 2022 - ACS Publications
The ability to continuously monitor the concentration of specific molecules in the body is a
long-sought goal of biomedical research. For this purpose, interstitial fluid (ISF) was …

Interfacial design and functionization on metal electrodes through self-assembled monolayers

D Chen, J Li - Surface Science Reports, 2006 - Elsevier
Self-assembled monolayers (SAMs) provide a convenient, flexible, and simple system with
which to tailor and functionalize the interfacial properties of metal electrodes. The SAMs on …

Quantifying thiol–gold interactions towards the efficient strength control

Y Xue, X Li, H Li, W Zhang - Nature communications, 2014 - nature.com
The strength of the thiol–gold interactions provides the basis to fabricate robust self-
assembled monolayers for diverse applications. Investigation on the stability of thiol–gold …

Preparation of electrode-immobilized, redox-modified oligonucleotides for electrochemical DNA and aptamer-based sensing

Y Xiao, RY Lai, KW Plaxco - Nature protocols, 2007 - nature.com
Recent years have seen the development of a number of reagentless, electrochemical
sensors based on the target-induced folding or unfolding of electrode-bound …

Label-free, real-time monitoring of cytochrome C drug responses in microdissected tumor biopsies with a multi-well aptasensor platform

TNH Nguyen, LF Horowitz, T Krilov, E Lockhart… - Science …, 2024 - science.org
Functional assays on intact tumor biopsies can complement genomics-based approaches
for precision oncology, drug testing, and organs-on-chips cancer disease models by …

A label-free impedimetric aptasensor for the detection of Bacillus anthracis spore simulant

V Mazzaracchio, D Neagu, A Porchetta… - Biosensors and …, 2019 - Elsevier
Herein, we report an impedimetric DNA-based aptamer sensor for a single-step detection of
B. anthracis spore simulant (B. cereus spore). Specifically, we designed a miniaturized label …

Label-free capacitive assaying of biomarkers for molecular diagnostics

BL Garrote, A Santos, PR Bueno - Nature Protocols, 2020 - nature.com
The label-free analysis of biomarkers offers important advantages in developing point-of-
care (PoC) biosensors. In contrast to label-based methodologies, such as ELISA, label-free …

Impedance biosensor for peanut protein Ara h 1

Y Huang, MC Bell, II Suni - Analytical chemistry, 2008 - ACS Publications
A reagentless electrochemical impedance biosensor for detection of peanut protein Ara h 1,
one of the allergenic proteins found in peanuts, has been demonstrated using an Au …