TCM “medicine and food homology” in the management of post-COVID disorders

CYJ Ng, HH Bun, Y Zhao, LLD Zhong - Frontiers in Immunology, 2023 - frontiersin.org
Background The World Health Organization declared that COVID-19 is no longer a public
health emergency of global concern on May 5, 2023. Post-COVID disorders are, however …

Molecular mechanistic pathways targeted by natural compounds in the prevention and treatment of diabetic kidney disease

K Zhou, X Zi, J Song, Q Zhao, J Liu, H Bao, L Li - Molecules, 2022 - mdpi.com
Diabetic kidney disease (DKD) is one of the most common complications of diabetes, and its
prevalence is still growing rapidly. However, the efficient therapies for this kidney disease …

Gastrodin alleviates cisplatin nephrotoxicity by inhibiting ferroptosis via the SIRT1/FOXO3A/GPX4 signaling pathway

CW Qiu, B Chen, HF Zhu, YL Liang, LS Mao - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Cisplatin (CP) results in acute kidney injury (AKI) and
negatively affects patients' therapy and survival. The dried rhizome of Gastrodia elata Blume …

[HTML][HTML] Inhibition of oxido-inflammatory and apoptotic pathway is involved in the protective effect of Ginkgo biloba supplement in cyclosporine-A induced vascular …

JN Asiwe, SI Ovuakporaye, B Ben-Azu… - Pharmacological …, 2023 - Elsevier
Abstract Background Cyclosporine (Cs-A), an immunosuppressant drug used to prevent
organ rejection in patients receiving organ transplants, has been linked to cardiovascular …

Gastrodin destabilizes survivin and overcomes pemetrexed resistance

J Liao, X Qing, G Deng, Y Xiao, Y Fu, S Han, X Li… - Cellular …, 2023 - Elsevier
Survivin is a bifunctional protein that plays crucial roles in tumorigenesis. In the present
study, we discovered that the natural product gastrodin suppressed the cell viability and …

Gastrodin attenuates angiotensin II-induced vascular contraction and MLCK/p-MLC2 pathway activation

Z Guo, X Yang, M Wu, A Shen, J Li, X Zhang… - Pharmaceutical …, 2023 - Taylor & Francis
Context Gastrodin has been used as antihypertension therapy in China; however, the
mechanisms underlying the effects of gastrodin have yet to be fully elucidated. Objective To …

[HTML][HTML] A comparative study of vestibular improvement and gastrointestinal effect of betahistine and gastrodin in mice

YX Zhang, HX Wang, QX Li, AX Chen, XX Wang… - Biomedicine & …, 2022 - Elsevier
Betahistine and gastrodin are the first-line medications for vestibular disorders in clinical
practice, nevertheless, their amelioration effects on vestibular dysfunctions still lack direct …

Gastrodin Induces Ferroptosis of Glioma Cells via Upregulation of Homeobox D10

W Cao, J Lan, Z Zeng, W Yu, S Lei - Molecules, 2023 - mdpi.com
Gastrodin, the primary bioactive compound found in Gastrodia elata, has been shown to
exhibit neuroprotective properties in a range of neurological disorders. However, the precise …

Potential Targets and Action Mechanism of Gastrodin in the Treatment of Attention‐Deficit/Hyperactivity Disorder: Bioinformatics and Network Pharmacology Analysis

Z Song, G Luo, C Han, G Jia… - … and Alternative Medicine, 2022 - Wiley Online Library
Objective. Gastrodin is a main medicinal component of traditional Chinese medicine (TCM)
Gastrodia elata Blume (G. elata), presenting the potential for the treatment of attention …

[PDF][PDF] Association of Metabolic Syndrome or Weather Conditions with the Severity and Prognosis of Sudden Sensorineural Hearing Loss

Y Xu, Y Zhang, Q Yan, C Chen, B Zhu, Y Wang - J Int Adv Otol, 2024 - advancedotology.org
BACKGROUND: It is reported that sudden sensorineural hearing loss (SSNHL) is closely
related to diabetes, hypertension, and hyperlipidemia. While the metabolic syndrome (MetS) …