The development of a massively producible vaccine against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, is essential for stopping the …

This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …

The SARS-CoV-2 virus, implicated in the COVID-19 pandemic, recognizes and binds host
cells using its spike glycoprotein through an angiotensin converting enzyme 2 (ACE-2) …

The Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) has been identified
as a promising blood-stage candidate antigen to include into a broadly cross-reactive …

Over 35 years since it was established to make recombinant proteins, the baculovirus
expression vector system continues to develop and improve. Early systems for recombinant …

The nature of enveloped virus-like particles (VLPs) has triggered high interest in their
application to different research fields, including vaccine development. The baculovirus …

The use of lentiviral vectors (LV) in gene therapy has been growing in recent years. To meet
the increasing clinical demand, LV production platforms will benefit from improved …

Stable cell pools are receiving a renewed interest as a potential alternative system to clonal
cell lines. The shorter development timelines and the capacity to achieve high product yields …

Proteins are synthesized in heterologous systems because of the impossibility to obtain
satisfactory yields from natural sources. The efficient production of soluble and functional …

ABSTRACT Introduction: Influenza Virus-like Particles (VLPs) are one of the most promising
vaccine strategies to complement traditional egg-based processes and contribute to …