Critical overview on endocrine disruptors in diabetes mellitus

C Hinault, P Caroli-Bosc, F Bost… - International journal of …, 2023 - mdpi.com
Diabetes mellitus is a major public health problem in all countries due to its high human and
economic burden. Major metabolic alterations are associated with the chronic …

Is arsenic exposure a risk factor for metabolic syndrome? a review of the potential mechanisms

P Pánico, M Velasco, AM Salazar, A Picones… - Frontiers in …, 2022 - frontiersin.org
Exposure to arsenic in drinking water is a worldwide health problem. This pollutant is
associated with increased risk of developing chronic diseases, including metabolic …

Arsenic-induced lung inflammation and fibrosis in a rat model: Contribution of the HMGB1/RAGE, PI3K/AKT, and TGF-β1/SMAD pathways

W Wang, F Zheng, A Zhang - Toxicology and Applied Pharmacology, 2021 - Elsevier
An increasing number of studies have shown that arsenic exposure increases the risk of
lung cancer as well as a variety of non-malignant respiratory diseases, including bronchitis …

AS3MT facilitates NLRP3 inflammasome activation by m6A modification during arsenic-induced hepatic insulin resistance

T Qiu, C Wu, X Yao, Q Han, N Wang, W Yuan… - Cell Biology and …, 2023 - Springer
Abstract N6-methyladenosine (m6A) messenger RNA methylation is the most widespread
gene regulatory mechanism affecting liver functions and disorders. However, the …

Association between heavy metals, metalloids and metabolic syndrome: new insights and approaches

AC Martins, B Ferrer, AA Tinkov, S Caito… - Toxics, 2023 - mdpi.com
Metabolic syndrome (MetS) is an important public health issue that affects millions of people
around the world and is growing to pandemic-like proportions. This syndrome is defined by …

Arsenic-protein interactions as a mechanism of arsenic toxicity

CA Vergara-Gerónimo, AL Del Río… - Toxicology and Applied …, 2021 - Elsevier
Millions of people worldwide are exposed to arsenic, a metalloid listed as one of the top
chemical pollutants of concern to human health. Epidemiological and experimental studies …

Hepatoprotective and anti-hyperglycemic effects of ferulic acid in arsenic-exposed mice

M Daryagasht, M Moosavi, L Khorsandi… - Food and Chemical …, 2023 - Elsevier
Arsenic is a toxic metalloid that increases the risk of hepatotoxicity and hyperglycemia. The
objective of the present study was to assess the effect of ferulic acid (FA) in mitigating …

Prevalence of type 2 diabetes mellitus in relation to arsenic exposure and metabolism in Mexican women.

K Rangel-Moreno, B Gamboa-Loira… - Environmental …, 2022 - Elsevier
Background Experimental studies have shown the diabetogenic potential of inorganic
arsenic (iAs); however, the epidemiological evidence is still inconclusive. This could be …

[HTML][HTML] NAC antagonizes arsenic-induced neurotoxicity through TMEM179 by inhibiting oxidative stress in Oli-neu cells

Z He, Y Zhang, H Zhang, C Zhou, Q Ma, P Deng… - Ecotoxicology and …, 2021 - Elsevier
Arsenic is one of the most common environmental pollutants. Neurotoxicity induced by
arsenic has become a major public health concern. However, the effects of arsenic-induced …

Molecular and metabolic analysis of arsenic-exposed humanized AS3MT mice

J Todero, C Douillet, AJ Shumway… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Chronic exposure to inorganic arsenic (iAs) has been associated with type 2
diabetes (T2D). However, potential sex divergence and the underlying mechanisms remain …